Addy Brown had 18 points and eight rebounds, Sienna Betts had 11 points, 10 rebounds and three blocks and No. 10 UCLA never trailed Thursday night in a 76-44 win over Arizona on Thursday.
Timea Gardiner added 16 points, KK Bransford scored 13 and Somto Okafor 10 for UCLA (3-0).
Makayla Presser-Palmer and Aliyahna Morris led Arizona (2-1) with eight points apiece.
Betts made back-to-back baskets before Donovyn Hunter hit a three-pointer that made it 14-4 a little more than four minutes into the game and the Bruins took a 13-point lead into halftime.
Sumayah Sugapong hit a three-pointer and Gerda Raulusaityte followed with a layup 48 seconds into the second half that made it 37-29 but the Wildcats got no closer.
Brown had a three-point play and hit a three-pointer as part of a a 16-2 run that closed the third quarter and gave UCLA a 62-39 lead going into the fourth.
The Wildcats scored just 19 second-half points, five in the fourth quarter — their lowest-scoring quarter this season. Arizona shot 24% (14 of 58) overall, made just three of 16 (19%) from three-point range, and hit 13 of 19 (68%) from the free-throw line.
The Bruins have won four straight against Arizona and lead the all-time series with their former Pac-12 rival 67-25.
Up next for UCLA: vs. Princeton at Pauley Pavilion on Sunday.