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Meow Wolf is getting closer to unveiling its Los Angeles locale. When doors open — the company is targeting late 2026 — anticipate a walk-around, floor-to-ceiling experience that pays homage to the art of cinema with a sci-fi, psychedelic-like bent.

And to bring that vision to life, the Santa Fe, N.M.-based experiential art collective will be working with nearly 40 L.A. artists across multiple mediums. Expect more than a dozen sculptural and diorama artists to contribute, along with those who specialize in mixed media for interactive and video content. Local artists will also create a number of murals for the space, and a handful of artists have been chosen to curate their own life-size rooms in the venue at West L.A.’s Howard Hughes entertainment complex.

Artist Gabriela Ruiz will be contributing a major piece to Meow Wolf L.A.

(Jason Armond / Los Angeles Times)

While the bulk of a Meow Wolf exhibition is envisioned and designed by a core in-house team in Santa Fe, the company partners with dozens of local artists in each city to ensure a local flavor. Here in Los Angeles, the task of curating L.A. artists fell heavily to Han Santana-Sayles. As a SoCal native from a Mexican American family, Santana-Sayles has told me, “I would be dishonored” if the exhibit failed in its mission to capture the breadth of the L.A. population.

“It’s really important to make that intentional,” Santana-Sayles said. “I’m not just going out and saying, ‘They have art I like. I’m going to bring them in.’ It’s a combination. Yes, they’re an amazing artist, and they have a really important story for this region.”

Santana-Sayles worked closely with art curator AJ Girard as Meow Wolf’s local art liaison. Girard has spoken of being inspired by everything from L.A.’s emphasis on social media to commercialism to graffiti art.

“Social media and social capital is so relevant in our city,” Girard said. “How do we make fun of it in an avant-garde, punk, radical way? How do we poke holes at it?”

Artists tapped to create full-scale rooms at Meow Wolf L.A. include Gabriela Ruiz, who crafted an adorably vibrant, multicolored insect that will serve as a periscope, and collective Everything Is Terrible, who described their space as featuring a “cartoony, root vegetable floating alien god.”

Also look for contributions from Compton’s Charles E. Dickson, a renowned self-taught sculpture artist, whose public works can be found throughout the region, including at Metro’s Mariposa Station and outside the California African American Museum, and Jen Stark, whose geometric kaleidoscope art flirts with the natural and the synthetic. Stark’s “Chromatic Cascade” is a staple of downtown’s Art’s District.

Lauren YS (a.k.a Squidlicker) is also tapped to have a room at Meow Wolf L.A., known for hyper-vivid colors and surrealist mythology. The artist currently has a piece in “Mythical Creatures: The Stories We Carry” at the USC Pacific Asia Museum.

Downtown L.A. street artist S.C. Mero will be contributing a sculpture piece to Meow Wolf L.A.

(Kayla Bartkowski / Los Angeles Times)

Others with exhibiting rooms include Wayne White, album artist, surrealist and puppeteer, perhaps best known for his work as the main puppet-maker for the children’s show “Pee-wee’s Playhouse; Seth Bogart, known best as a local musician (Hunx and his Punx); upcycled fashion specialist Corinne Loperfido; cartooney psychedelic artist Killer Acid; and longtime Meow Wolf contributor Nick Toll.

Meow Wolf L.A. lists seven artists as contributing either video installations and games to the space, including artist/musician Vinyl Williams and musician/animator Hugo Shiboski with director/media artist Will Wharton. Animators Réka Bucsi, Agnus Oakes and Cadmiumcoffee, as well as digitial artist Blake Kathryn will also contribute. It was previously announced that local animation house Titmouse would be supplying media for Meow Wolf L.A.

Six artists are slated to paint murals for Meow Wolf L.A. Look for work from Bunnie Reiss, Ozzie Juarez, Greg Ito, Harlen Hue, Evelyn Tan and Devin Reynolds.

Finally, more than a dozen L.A. artists are listed as contributing either sculptures or dioramas to the exhibition. Those artists range from downtown L.A. street artist S.C. Mero to multidisciplinary artist Ruben Ulises to former Coachella Valley Music & Arts Festival contributor Sofia Enriquez.

Rounding out the list will be David Altmejd, Sharif Farrag, Joe Holliday, Nemo Gould, Alake Shilling, Elrod, Brooke Weston, Shrine, Hana Ward, Roberto Benavidez, Estevan Oriol, Wizard of Barge, Mike Chattem and Karla Ekaterine Canseco.

Meow Wolf helped define the modern immersive space. Since 2016, when the once-scrappy Meow Wolf opened Santa Fe’s “House of Eternal Return” exhibition, the company has welcomed about 10 million visitors across its four venues in locales such as Las Vegas, Denver, Houston and the Dallas suburbs.

For its upcoming Los Angeles venue, experiential art firm Meow Wolf will focus on the art of storytelling, with a specific eye toward spoofing our city’s moviemaking magic. To help bring that vision to life, Meow Wolf has entered into a creative partnership with Titmouse, one of L.A.’s most renowned independent animation houses.

The Hollywood-based studio behind popular series such as “Big Mouth” and “Star Trek: Lower Decks” will create animation that will be shown throughout the West L.A. venue, which is on target for a late 2026 opening at the Howard Hughes entertainment complex.

It’s a move that represents a shift for Santa Fe, N.M.-based Meow Wolf. Over the last decade-plus, the art collective has grown beyond its anything-goes, punk-meets-psychedelic roots into an organization with full-scale, maximalist installations in its hometown, Denver, Las Vegas, Houston and the Dallas suburbs. In the past, Meow Wolf kept most of its media in-house.

As part of its larger-than-life participatory art installations, Meow Wolf L.A. will feature a mix of live action and animation, the former filmed by Meow Wolf in its Santa Fe studio. Meow Wolf’s James Stephenson, a senior VP with the company and its creative director of emerging media, said the degree to which the L.A. exhibition will lean into various animation styles necessitated an outside partner. Titmouse’s work, in development by a number of directors with contrasting tones, will be shown on a variety of formats, ranging from cinema screens to full-room projections.

“I really believe in animation as an art form, and I know the Titmouse folks do too,” Stephenson says. “Animation is made by artists. It’s made by artists with their own hands. It’s something that is still very rooted in craft.”

Meow Wolf’s L.A. space is set in a former cinema complex, and will champion its location, taking guests on a journey through a converted movie house and beyond, into a sci-fi-inspired fantasyland with sentient spaceships and a 30-foot-tall mushroom tower. Meow Wolf creatives have spoken of the fantastical movie theater as one that will feature animated, self-aware candy before attendees enter the main exhibition space, making Titmouse’s work some of the first art guests will encounter. Titmouse co-founder Chris Prynoski has said the studio has lined up at least six directors for the exhibit.

An in-progress art installation destined for Meow Wolf L.A. at the art collective’s Santa Fe, N.M., headquarters. The L.A. exhibition will feature animation from Titmouse.

(Gabriela Campos / For The Times)

Titmouse, says Stephenson, is the right partner because “they’re known less for a house style, and more for a house vibe.” Over the years, Titmouse has been behind such diverse shows as “Scavengers Reign,” owning a Jean Giraud influence rooted in French and Spanish surrealism, the lively “Jentry Chau vs. the Underworld,” with an unique color palette that took inspiration from anime and Chinese mythology, the exaggerated comic book feel of Adult Swim’s “Metalocalypse,” and the approachable yet expressive tone of “Star Trek: Lower Decks.”

“Meow Wolf’s vibe is similar to Titmouse’s vibe,” Stephenson says. “It’s artist-first, artist-driven, independent and kinda edgy. They are always trying to find the edge of what’s possible. They try to see how far they can go, and it’s done for fun and in the spirit of taking risks.”

Prynoski says working with Meow Wolf will give Titmouse a sense of artistic freedom it doesn’t always have when delivering content for more traditional Hollywood partners. He says the multi-director approach is a callback to the early days of Warner Bros. Animation, when individual creators put their own stamp on Looney Tunes material.

“I use Bugs Bunny as an example,” Prynoski says. “You’ve got a Friz Freleng Bugs Bunny short. You’ve got a Chuck Jones Bugs Bunny short. You’ve got a Tex Avery Bugs Bunny short. They’re all different versions of Bugs Bunny, and people who are really paying attention can tell which director directed each one. Even though to the layman, these are all Bugs Bunny, but if you lined them up, they are drawing in different styles, sensibilities and techniques.”

Prynoski says that was a centerpiece of his pitch to Meow Wolf, noting that characters will reappear in multiple installations, each handled by a different artist. Meow Wolf L.A., in fact, will be the firm’s most character-driven exhibition, as guests will follow the storylines of three main protagonists throughout the space.

In announcing the partnership, Meow Wolf and Titmouse released an image from an animated work directed by Luca Vitale. It features a key character having a moment with a hummingbird and it’s done in an elegant, slightly anime-influenced style. It’s an image full of movement, reflecting a character in transition with inviting pastels and bold dashes.

“I like that image because I think it captures some of the sense of wonder that we want people to feel,” Stephenson says. “The character is having an encounter with the elusive nature of creativity and reality in a way that makes them have a different perspective of what’s possible.”

Other contributing animation directors to Meow Wolf L.A. include Space Dawg, Felix Colgrave, Alexander Vanderplank and Philémon Martin, and Jun Ioneda.

Titmouse’s partnership with Meow Wolf will extend beyond the L.A. exhibition. The two will be working on the development of Meow Wolf New York, which is slated to open some time after Los Angeles, and are collaborating on a planned animated series, which Prynoski is spearheading.

Meow Wolf exhibits are the result of sometimes hundreds of disparate artists coming together in a shared space. Distilling that into a signature, singular style for a series could be a challenge. Stephenson pinpoints some guiding principles.

“You really need to feel the hand of the artist,” he says. “You need to feel a DIY aesthetic. You need to feel the materiality. Those are very specific to what we are.”