News Desk

F-35s Quarterbacking Drones Seen As Gateway To USMC’s 6th Gen Fighter

The U.S. Marine Corps says it is making good progress toward fielding Collaborative Combat Aircraft (CCA) type drones, starting with a landing gear-equipped version of Kratos’ XQ-58 Valkyrie. The service sees those aircraft, and potentially other CCAs, paired with its F-35s as a “bridge” to an entire family of next-generation air combat capabilities, which could include a sixth-generation crewed fighter.

Marine officials discussed the service’s CCA plans and broader future aviation vision during a panel discussion at the Navy League’s Sea Air Space 2026 exhibition, at which TWZ is in attendance. The Corps’ CCA efforts currently fall under a program called Marine Air-Ground Task Force (MAGTAF) Uncrewed Expeditionary Tactical Aircraft (MUX TACAIR). The MAGTAF is the primary organizing concept around which the service deploys air and ground forces.

“So, with the MUX TACAIR effort, I think we’re meeting our testing goals. I would say that it’s on track,” Marine Col. Dan Weber, the Unmanned Aerial Systems Branch Head in the office of the Deputy Commandant for Aviation, said. “From a funding and demand power perspective, I think we’ve got great support. We’ve got good partners. We’ve got good relationships right now to keep that program on track, and I expect that we’re going to meet all of our milestones and goals.”

A landing gear-equipped version of Kratos’ XQ-58 Valkyrie, like one seen rendered here, is set to be the Marine Corps first operational CCA-type drone. Kratos

“From the F-35 side, the vision ultimately is we want the F-35 to be a quarterback with CCAs as attritable mass, as enablers to ensure the MAGTAF can project power, the sensing, the lethality, [and] all of the intangibles that kind of go along with that,” Marine Col. Thomas Bolen, the Tactical Aviation (TACAIR) Branch Head, another one of the panelists, also said. “How we integrate with CCAs is going to be extremely important, and that will bridge us down the road to kind of the sixth-generation family of systems.”

One of the “main things in our portfolio that will be enduring and developing over the next couple years” is “man-unmanned teaming,” Marine Col. Richard Rusnok, head of the Cunningham Group, who was also on the panel, added. “We’re laying the foundation for that with our first foray into Collaborative Combat Aircraft, the MQ-58.”

The Cunningham Group, which also falls under the office of the Deputy Commandant for Aviation, is charged with plotting out the overarching future vision for Marine Corps aviation.

MQ-58 refers to Marine-specific variants of Kratos’ Valkyrie now in development. Last year, the Corps announced that it was transitioning what had originally been experimental work with a small fleet of XQ-58s into a full program of record to acquire an operational platform. Kratos has since partnered with Northrop Grumman to deliver these uncrewed aircraft.

A Marine XQ-58 flies together with a pair of US Air Force F-35As during a test. USAF

Marine Valkyries will have built-in landing gear, unlike the original version of the drone, but will still be capable of making rocket-assisted takeoffs from static launchers. This means the uncrewed aircraft will retain a valuable degree of runway independence, but that there will also be tradeoffs, as TWZ has previously explored here.

In January, Kratos told TWZ it was hoping to see the first flight of a landing gearing-equipped Valkyrie in early 2026, but there has been no official announcement yet of that milestone being reached. The Marine Corps’ unclassified 2026 Aviation Plan presents the MQ-58 as a capability arriving in the 2026 to 2030 timeframe.

The Marine Corps included this graphic in its 2026 Aviation Plan showing general timelines for various planned capabilities, including multiple tranches of MUX TACAIR drones. USMC

The Marines have also said previously that they expect the MQ-58 to be just the first in a planned series of CCA “increments,” which might entail the future acquisition of completely different types of drones. The service has said in the past that MUX TACAIR, broadly speaking, “will enhance Marine Corps Aviation’s lethality and ability to support the Stand-in Force (SiF) by delivering air-to-ground, reconnaissance, and Electronic Warfare (EW) capabilities.”

The Corps has also already chosen to use General Atomics’ YFQ-42A Dark Merlin at least as a surrogate to test new autonomy technologies and other mission systems under the umbrella of the MUX TACAIR program. The YFQ-42A is also one of two drones under development as part of Increment 1 of the U.S. Air Force’s CCA program. Dark Merlins have been flying since August 2025, but General Atomics announced an indefinite pause in flight activities earlier this month after one of the drones suffered an accident on takeoff.

A YFQ-42A seen during a flight test. General Atomics

Speaking on the panel today, Col. Thomas Bolen did not elaborate on what the Marine Corps’ “sixth-generation family of systems” might consist of. However, Marine Lt. Gen. William Swan, the Deputy Commandant for Aviation, said his service was beginning to explore what it might want in a future sixth-generation crewed combat jet during a press roundtable last week, as first reported by Breaking Defense.

“Last year’s Av[iation] Plan didn’t have six-gen on there, and I made the team put it on, because we need to think about that,” Swan said at that time. “We’re not there yet. We’re fast following with the Air Force, right? They got the F-47. The Navy’s looking at F/A-XX, and they’re just starting on that. So we are going to watch.”

A rendering of Boeing’s submission for F/A-XX. Boeing is also the prime contractor for the US Air Force’s F-47. Boeing

“We want to be an all Block 4 F-35 fleet, and that’s probably going to take another 10 years. So we’re probably five to 10 years away from ultimately making that decision. And we’ll see what they have, see what the threat looks like,” Swan continued. “I think right now, if you had to say, ‘hey, what is it going to look like?’, I think it’ll look a lot more like what the Navy’s doing, because we still fly off the carriers, we’re part of the Department of the Navy.”

“I don’t know that we’re going to get high-end, and that’s really not a Marine Corps mission; it’s the Air Force,” he added. “So I think if I had to – if you said, make a decision right now, it would be yes, some amount to augment the fifth-gen [F-35] force, and it would probably look something like the F/A-XX, or whatever the Navy ends up being [sic; acquiring].”

A rendering of Northrop Grumman’s F/A-XX proposal. Northrop Grumman

Lt. Gen. Swan, who served as the moderator for today’s panel at Sea Air Space, as well as Col. Bolen, again stressed the importance of the Block 4 upgrades for the F-35, including for future teaming with CCAs. The Block 4 effort has been mired in delays and cost growth, even after a revision in the fielding strategy last year to focus first on a truncated portion of the planned capability improvements. The full package for all three Joint Strike Fighter variants is eventually expected to include a new AN/APQ-85 radar and electronic warfare suite, replacements for the AN/AAQ-37 Distributed Aperture System (DAS) and Electro-Optical Targeting System (EOTS), and a host of other improvements. A particular point of concern now is that new production F-35s might soon start being delivered without any radars at all, as a result of issues tied to the development of the APG-85.

As the Marine’s top aviation officer noted last week, it could be 10 years before his service at least sees all of its F-35s fully upgraded to the Block 4 standard. That, in turn, could have serious impacts on the service’s broader plans to acquire and field new crewed and uncrewed aircraft.

A view of the F-35 production line. Lockheed Martin

Marine Corps interest in whatever the Navy chooses for F/A-XX could be an important factor for the future of that program, as well. In response to a question from TWZ at a roundtable on the sidelines of Sea Air Space this morning, Chief of Naval Operations Adm. Daryl Caudle said he is now hoping to see the selection of the winning design in the F/A-XX competition by August. The program has been in bureaucratic purgatory since the Pentagon moved to effectively shelve it indefinitely last year, with Congress subsequently intervening to keep it funded. How the Navy’s next-generation carrier-based fighter plans will proceed now still very much remains to be seen.

If nothing else, the vision the Marines have put forward today clearly frames Block 4 F-35s ‘quarterbacking’ fleets of CCAs as a key stepping stone to the service’s next-generation aviation capabilities.

Contact the author: joe@twz.com

Joseph has been a member of The War Zone team since early 2017. Prior to that, he was an Associate Editor at War Is Boring, and his byline has appeared in other publications, including Small Arms Review, Small Arms Defense Journal, Reuters, We Are the Mighty, and Task & Purpose.


Source link

I’m A Celebrity’s Gemma Collins and David Haye out in double eviction as campmates stunned

David Haye and Gemma Collins have been booted out of I’m A Celebrity in a shock double exit, leaving their fellow campmates reeling – and closer to being named King or Queen of the jungle

David Haye and Gemma Collins have been booted out of I’m A Celebrity in a shock double exit.

Fans were stunned to see two of the camp’s biggest personalities leave the ITV jungle show. The pair have both hit the headlines during their time on the show – but for very different reasons.

They were booted out of camp tonight, decided by their fellow campmates and their departure will no doubt change camp considerably. Speaking after his exit, David said: “I’m ok. I’m happy. I’ve had an amazing time, great new friends and lots of experiences. You’ve cranked up the trials and the challenges. Ten days it was fun, I enjoyed it.

“Today and yesterday people started cracking, there was a bit more beef between people. Me and Adam had a bit of back and forth, but the banter, he didn’t really like the banter, he kind of got to the limit he was willing to receive.”

Asked if he pushed it too far, he added: “Probably… I’m an extremist and I can’t help myself. It’s all love, I love him really. He’s a cool guy. It’s all perfect now.”

Gemma also opened up on her departure, explaining how she has no bad feelings towards David.

“I’ve got no bad feelings to David, everyone has their time. I’m so happy I’ve got to relive this whole experience again ,last longer, i was much more determined this time and had a lot to prove,” he said.

“Just to do a trial was such a moment in my life because I never thought I could do it. It’s always easy to be outwardly confident but sometimes inside you’re a little bit less confident. I’m going back GI Jane, I’m going back yeah baby. God knows what I’m going to do next. I just don’t think I’ll be as scared of everything.”

Gemma had previously described her time on All Stars as “redemption” after she quit days into the first series.

“Going on All Stars is a real moment for me in my career – it’s redemption. To be able to do this again is the greatest honour ever. I am going to be the best campmate and get those stars. None of us will be starving under my watch,” she said.

“I am dreading the whole lot, I don’t think anyone goes into the jungle going ‘woohoo’. It’s not normal to be faced with animals, but I am going in as Gemma Collins. Gemma Collins is a self-made woman. I have been to hell and back to get to where I am today. I am just looking forward to proving to people I can do it.”

David, meanwhile, has caused quite a stir during his time on the show, firstly for comments about calling his girlfriend the “personality of a proper ugly bird”.

In a rant, he said: “Most ugly girls realise they don’t they’re not pretty enough to… they gotta have a personality to banter and to tell jokes and s**t, so people overlook the fact that they’re not aesthetically amazing, straight away. Which is what’s called Ugly Duckling syndrome, where girls are ugly, when they start off, and then they and then they kind of they, they get pretty as they get older. But they still got the personality of when they’re ugly. Does that make sense?”

David also recently came under fire for his comments to Adam Thomas, which exploded even more this evening.

With two of the biggest personalities now go, how will it change the camp for the remainder of the show?

Like this s tory? F or more of the latest showbiz news and gossip, follow Mirror Celebs on TikTok , Snapchat , Instagram , Twitter , Facebook , YouTube and Threads .



Source link

2 killed in mass shooting near North Carolina middle school

April 20 (UPI) — Two people were killed Monday in a shooting near a North Carolina middle school where two children agreed to meet for a fight, police said.

Law enforcement officials were alerted to a fight at Leinbach Park on Robinhood Road near Jefferson Middle School in Winston-Salem, N.C., at 9:52 a.m. EST. As officers were on the way to the scene, the call was upgraded to a shooting.

The Winston-Salem Police Department posted on Facebook that “two young individuals” met at Leinbach Park for a “planned fight.” When those individuals arrived, “the situation escalated significantly, leading to multiple people exchanging gunfire.”

The police department didn’t say how many people were injured in the shooting, but used a hashtag for “mass shooting” in its post on X.

“Several individuals — both victims and suspects — have been identified and located,” the Winston-Salem Police Department posted on social media. “Due to the number of people involved, efforts are ongoing to account for everyone. At this time, some of those involved in the incident are juveniles.”

Police advised that nearby schools were operating on a normal schedule, but community members were urged to avoid the area to allow emergency responders to operate safely at the scene. The park and two nearby roads were closed as officers processed the scene.

“This is an isolated incident and remains under active investigation,” the police department said.

Source link

Chávez the Radical XXXII: ‘The Bonus-over-Wage Policy Pulverized Incomes’

Once he got into power, Hugo Chávez spared no effort to reverse the neoliberal policies implemented in the 80s and 90s. This meant impressive advances for the Venezuelan working class.

In this 2006 speech, Chávez paid special attention to the Fourth Republic’s policies to increase the precariousness of the workers and favor business interests, particularly by replacing wages with bonuses.

With the economy under merciless US attacks in recent years, the Venezuelan government has favored non-wage bonuses, sparking widespread debate within Chavismo and criticism from trade unions.

Source: Tatuy Tv



Source link

Christina Applegate shares health update after reported hospital visit

Christina Applegate is speaking out amid reports of an extended hospitalization.

The acclaimed comedy actor, who was diagnosed with multiple sclerosis in 2021, has been the subject of regular news coverage in the years since her health first began to decline. TMZ on Thursday reported that she had been hospitalized in Los Angeles for undisclosed reasons, leading her friends and fans to extend messages of support.

“Thank you for the outpouring of love and well wishes,” Applegate said Monday in a social media post seemingly referencing such messages. The post included a photo of the actor’s recently released memoir, “You With the Sad Eyes,” and a coffee mug resting on what appears to be a home parapet.

She continued: “Health issues are a constant for me, but I’m a strong chick and I’m getting stronger and better every day. I’m taking a moment to focus on my health, but I’ll be back with more to say soon enough.”

Several of Applegate’s fellow actors offered support in the comments section, with Cheyenne Jackson writing, “Christina, just in case today’s mail got lost: We the public would like to formally submit that we adore you, support you, and RIDE AT DAWN FOR YOU ALWAYS.”

“Days of Our Lives” star Greg Rikaart echoed his sentiment: “Can’t think of anyone the collective culture roots for more than you.”

Applegate’s representative previously declined to comment on the hospitalization reports, telling Entertainment Weekly that the “Married … With Children” alum has “had a long history of complicated medical conditions that she has been refreshingly open about, as evidenced in her memoir and on her [‘MeSsy’] podcast.”

Applegate in March released “You With the Sad Eyes,” detailing everything from her unstable childhood to her decades-spanning acting career and the health issues that have plagued it.

“This book is not cathartic for me — let’s just go there,” Applegate recently told The Times. “I just needed to dump this s— out somewhere. It’s almost like you guys are now my therapists in the world.”

“There’s going to be really f— horrible s— and then we’re going to have fun stuff — because that’s what my editor told me to have (that’s a joke!) — and crap again,” the “Dead to Me” star said. “That’s my life.”



Source link

European Markets Fall as US–Iran Tensions Reignite and Peace Hopes Fade

European stock markets slipped on Monday as investor sentiment weakened amid renewed tensions between the United States and Iran. The downturn followed the seizure of an Iranian cargo ship by US forces and Tehran’s vow of retaliation, raising fears that a fragile ceasefire nearing its expiry may collapse.

The situation has been further complicated by Iran’s rejection of fresh peace talks and ongoing uncertainty over maritime security in the Strait of Hormuz, a critical global energy route.

Market Reaction

The pan-European STOXX 600 index declined by 0.8%, reflecting broad-based caution across financial markets. Major indices also moved lower, with Germany’s DAX down 1% and France’s CAC 40 falling 0.9%.

Losses were concentrated in sectors sensitive to geopolitical risk. Travel and leisure stocks led declines, followed by banking and automobile shares, which also came under pressure. In contrast, energy stocks rose as oil prices surged, reflecting concerns about supply disruptions.

Oil and Energy Impact

Crude oil prices jumped sharply, with Brent crude rising more than 5% to around $95 a barrel. The increase reflects heightened fears of disruption in the Strait of Hormuz, through which a significant portion of global energy trade passes.

Energy-dependent European economies remain particularly sensitive to price volatility, adding to investor caution across broader markets.

Geopolitical Tensions

Market sentiment shifted sharply from the previous week’s optimism, when easing signals from the Strait of Hormuz had briefly boosted equities. That optimism faded quickly after renewed maritime incidents and political escalation.

The United States and Iran continue to exchange accusations over ceasefire violations, while diplomatic efforts appear increasingly uncertain. The rejection of fresh negotiations by Iran and continued US pressure have added to concerns that the conflict could intensify further.

Outlook

Financial markets remain closely tied to developments in the Middle East. With the ceasefire approaching its expiration and no clear diplomatic breakthrough in sight, volatility is expected to persist.

Investors are likely to remain cautious until there is greater clarity on both maritime security in the Strait of Hormuz and the future of US–Iran relations.

With information from Reuters.

Source link

‘4×20: Quick Hits’ review: Trailblazers and moments in pot history

For disputed reasons, April 20, abbreviated to 420, has become a day to celebrate marijuana; even if this is nothing you mark on your calendar, the collective culture is bound to remind you.

Weed is not what it used to be, which is to say illegal everywhere. (State laws may differ, but the federal government still disapproves.) Stoners are no longer useful as a comedy device, while pot’s countercultural meaning has dissipated as it’s been absorbed into the mainstream. According to the CDC, some 60 million American reported using it in 2022. Snoop Dogg is a beloved media figure (and, somehow, an Olympics commentator). Seth Rogen co-owns a cannabis company, Houseplant, that also sells coffee, furniture and incense. The paper you are reading has published weed-themed gift guides.

Now, Hulu, wholly owned by the Walt Disney Company, is marking the day (Monday) with “4×20: Quick Hits,” a frisky anthology comprising four 20-minute documentaries on pot-related subjects, with family-friendly figure Jimmy Kimmel as an executive producer. It’s less about the drug itself than the arts, crafts and enterprises it has inspired. Given where we are now, it’s not surprising that there’s a historical bent to the films, a look back to earlier times — certainly worse for some of the people profiled, who were targeted by and battled with the law in pursuit of their businesses and dreams — but one they regard with a kind of amused nostalgia.

All the films are affectionate, most are light-hearted and often comical. One, Todd Kapostasy’s “Bong Voyage,” about the rise and fall and rise of artisanal glassblower Jason Harris, is narrated by one of his creations and includes such dumb puns as “fine piece of glass.” Directed by Brent Hodge, “Highly Unlikely” is an entertaining, straightforward reminiscence of the making of “Harold & Kumar Go to White Castle,” though it is less about the stoner themes than how the film broke stereotypes in making two little-known Asian actors, John Cho and Kal Penn, the film’s stars. The adorable “The Legend of Ganjasaurus Rex,” directed by Alex Ross Perry, and nearly the premise for a Christopher Guest movie, recounts an act of community filmmaking in the late ‘80s in pot-growing Humboldt County, wherein locals created a monster movie in a proxy war with the authorities, and its inspirational afterlife.

More serious in tone is Kyle Thrash‘s “High Times,” which looks at the history of the pot-centric magazine, its drug smuggling founder Tom Forçade and his suicide. More compelling perhaps is his friend, Yippie co-founder and lifelong cannabis activist Dana Beal, who frames the film; we see him in the nearly present day on trial for drug trafficking, having been stopped in Idaho with 56 pounds of raw marijuana, and also on the streets of New York leafleting passersby with his daughter to “help us legalize weed worldwide.”

Whether or not cannabis itself interests you, each of these mini-docs is capable of holding your attention for 20 minutes — assuming you’re capable from your end — and, being as brief as they are, may well send you to learn more. (I don’t imagine they will send you to smoke pot if you don’t — they didn’t work on me, anyway — and, who knows, might even make one less inclined.) You might finally watch “Harold & Kumar,” or find Garberville on a map, or look to see how things are going for Beal, or discover whether the same John Holmstrom who once edited High Times is the same person who founded Punk magazine and drew covers for the Ramones’ “Rocket to Russia” and “Road to Ruin” albums. (He is.) “Ganjasaurus Rex,” in its 90-minute full length, is itself online to see, and, for those who celebrate, I don’t suppose there’s a better day to watch it.

Source link

Gonadorelin: Molecular Signaling, Temporal Dynamics, and Expanding Research Horizons

Gonadorelin, a decapeptide identical in sequence to gonadotropin-releasing hormone, is believed to occupy a foundational position in endocrine signaling research. Since its structural elucidation in the twentieth century, the peptide has served as a conceptual bridge between neurochemical signaling and systemic hormonal coordination within the research model.

Contemporary scientific discourse increasingly frames Gonadorelin not merely as a reproductive regulator, but as a finely tuned molecular signal whose rhythmic release, receptor interactions, and downstream cascades offer insight into broader principles of cellular communication, feedback regulation, and temporal encoding. This article explores Gonadorelin through a research-oriented lens, supporting  its molecular characteristics, signaling properties, hypothesized systemic roles, and emerging investigative domains. The discussion relies on established scientific knowledge while maintaining speculative language appropriate to ongoing inquiry.

Molecular Identity and Structural Considerations

Gonadorelin is a linear decapeptide composed of ten amino acids arranged in a highly conserved sequence across vertebrate species. This conservation has long intrigued researchers, as it suggests evolutionary pressure to preserve both structure and function. From a biochemical perspective, the peptide’s relatively small size belies its extensive signaling reach within the research model.

At the molecular level, Gonadorelin may be viewed as an archetypal neuropeptide, synthesized as part of a larger precursor molecule and subsequently processed into its active form. Its tertiary simplicity allows it to interact with a specific G protein-coupled receptor, commonly referred to as the gonadotropin-releasing hormone receptor. Research indicates that subtle alterations in amino acid composition or terminal modifications may significantly alter receptor affinity, signaling bias, and degradation kinetics. These observations have fueled interest in Gonadorelin analogs as experimental tools for probing receptor dynamics and intracellular signaling selectivity.

Receptor Interaction and Intracellular Signaling Cascades

The interaction between Gonadorelin and its receptor represents a classic model for ligand-receptor specificity in mammalian endocrine research. Upon binding, the receptor undergoes conformational changes that may activate multiple intracellular pathways, including phospholipase C signaling, calcium mobilization, and protein kinase activation. Rather than functioning as a simple on-off switch, Gonadorelin signaling appears to encode information through frequency and amplitude modulation.

Research suggests that pulsatile exposure to Gonadorelin might generate distinct intracellular responses compared to continuous exposure, even when total peptide availability remains constant. This phenomenon has positioned Gonadorelin as a central example in studies of temporal signaling, where timing itself becomes a biologically meaningful variable. Investigations purport that this temporal encoding may influence gene transcription patterns, receptor recycling, and cellular sensitivity over time.

Temporal Dynamics and Rhythmic Signaling

One of the most compelling research properties of Gonadorelin lies in its rhythmic release pattern. Unlike many signaling molecules that operate through steady concentrations, Gonadorelin appears to function optimally through discrete pulses. Scientific inquiry has long theorized that this pulsatility allows the mammalian model to maintain responsiveness while avoiding receptor desensitization.

From a systems biology perspective, Gonadorelin may serve as a model for understanding how oscillatory signals regulate complex physiological networks. Computational analyses and laboratory-based research models have explored how variations in pulse frequency, duration, and interval might translate into differential downstream signaling outcomes. These explorations extend beyond reproductive endocrinology, offering conceptual frameworks potentially relevant to circadian biology, metabolic regulation, and adaptive feedback systems as they prove relevant to mammalian models.

Genetic Regulation and Transcriptional Influence Research

Beyond immediate signaling cascades, Gonadorelin is thought to potentially exert a longer-term interaction with or modulation of gene expression. Research indicates that activation of its receptor may alter transcriptional programs associated with cellular differentiation, hormone synthesis, and receptor expression itself. This layered regulatory architecture suggests that Gonadorelin signaling may participate in both rapid and delayed regulatory loops within the research model.

Epigenetic considerations have also entered the conversation. Some investigations hypothesize that repeated Gonadorelin signaling might influence chromatin accessibility or transcription factor recruitment in target cells. While these concepts remain under active exploration, they underscore the peptide’s potential relevance to developmental biology and long-term cellular adaptation.

Possible Role in Neuroendocrine Integration Research

Gonadorelin seems to occupy a unique intersection between neural signaling and endocrine output. Synthesized within specialized neurons, the peptide appears to translate neural inputs into hormonal coordination. This positioning has encouraged researchers to use Gonadorelin as a proxy for studying neuroendocrine integration more broadly.

Research models have examined how external stimuli such as environmental cues, stress signals, and metabolic states might modulate Gonadorelin synthesis and release. These lines of inquiry suggest that the peptide may function as an integrative node, aligning internal physiological states with external conditions. Such hypotheses elevate Gonadorelin from a single-pathway regulator to a dynamic mediator of cell-wide coherence.

Investigative Implications in Endocrine Research Models

Within laboratory settings, Gonadorelin has been widely referenced as a molecule suited for evaluationg receptor responsiveness, signaling fidelity, and feedback regulation. Its well-characterized sequence and receptor interaction profile make it an ideal benchmark for experimental design. Researchers often employ Gonadorelin to calibrate assays measuring gonadotropin synthesis, second messenger generation, or transcriptional responses.

Beyond traditional endocrine studies, Gonadorelin has found relevance in comparative signaling research. By examining how different cell types respond to identical Gonadorelin stimuli, investigators gain insight into cell-specific signaling architectures and receptor coupling strategies. These approaches may inform broader theories of cellular specialization within multicellular models.

Emerging Hypotheses Beyond Reproductive Signaling

While historically associated with reproductive axis regulation, Gonadorelin has increasingly been discussed in the context of broader biological roles. Some research indicates that its receptor may be expressed in tissues not classically associated with gonadotropin regulation. This observation has led to hypotheses that Gonadorelin signaling might support processes such as cellular proliferation, differentiation, or metabolic coordination in context-dependent ways.

In systems-level analyses, Gonadorelin has been theorized to contribute to network stability by participating in feedback loops that extend beyond a single hormonal axis. These speculative models propose that the peptide’s rhythmic signaling might synchronize multiple physiological subsystems, thereby supporting cellular homeostasis under changing conditions.

Conclusion

Gonadorelin remains one of the most intellectually rich peptides in contemporary biological research. Far from being limited to a narrow endocrine function, the peptide embodies key principles of molecular signaling, temporal regulation, and systems integration within the mammalian model. Its conserved structure, rhythmic signaling properties, and multifaceted intracellular impacts continue to inspire investigation across disciplines ranging from neuroendocrinology to computational biology. Researchers interested in further studying this compound are encouraged to visit Core Peptides.

References

[i] Stamatiades, G. A., & Kaiser, U. B. (2017). Gonadotropin regulation by pulsatile GnRH: Signaling and transcriptional control.Endocrinology, 158(11), 3369–3380.
 https://doi.org/10.1210/en.2017-00425

[ii] Navarro, V. M., & Tena-Sempere, M. (2012). New insights into the control of pulsatile GnRH release.Frontiers in Endocrinology, 3, 48. https://doi.org/10.3389/fendo.2012.00048

[iii] Whitlock, K. E., & Schlarb, J. E. (2019). Is gonadotropin-releasing hormone neurons dispensable for reproductive neuroendocrine function?Journal of Neuroendocrinology, 31(1), e12696. https://doi.org/10.1111/jne.12696

[iv] Flanagan, C. A., & Manilall, J. D. (2017). Gonadotropin-releasing hormone receptors: Structure, ligand binding and intracellular signaling.Frontiers in Endocrinology, 8, 274. https://doi.org/10.3389/fendo.2017.00274

[v] Ohlsson, B. (2016). Gonadotropin-Releasing Hormone and its physiological and pathophysiological roles in relation to the structure and function of the gastrointestinal tract.European Surgical Research, 57(1-2), 22–33. https://doi.org/10.1159/000445717

Source link

Aubrey Plaza’s ‘Kevin’ imagines what happens to pets after a breakup

The co-creators of the new Prime Video series “Kevin” tried to make the show “as personal as possible,” says Joe Wengert, explaining that he and Aubrey Plaza looked back to the end of their relationship nearly two decades ago for inspiration. Then, Wengert says, they focused on “the emotional story and investing in the inner lives” of the main characters. (Plaza’s production partner, Dan Murphy, was a third co-creator.)

And, Plaza adds, they strived to give the show a real “groundedness” in its specific New York neighborhood — Astoria, Queens, where she and Wengert lived together — while also “infusing some of my film nerdiness and love of New York films.” There’s even a rooftop scene that’s a homage to Al Pacino’s first leading film role, in “The Panic in Needle Park.”

OK, so all of that’s totally true, but “Kevin” is mostly a silly, raunchy animated series with a star-studded comedy cast about talking animals and their escapades in a life generally free of human owners.

The show opens with a couple, Dan (Mike Mitchell) and Dana (Plaza), breaking up and their cat, Kevin (Jason Schwartzman), deciding he’s done with both humans and will find his own way in the world.

“Joe and I were talking and realized we both weirdly wanted to do a cat comedy, and he had this idea and I loved it,” Plaza says, explaining that when they broke up, Kevin and another cat, Howard, passively went with Wengert. (Howard died relatively young, but, spoiler alert, Plaza says a cat named Howard will make an appearance as a tribute.)

“Joe was then doing a lot of comedy about being a single guy with cats.”

Wengert, who serves as showrunner, says the breakup was “a significant moment in my life” and he wanted to explore that, but a sad man going off to reconnect with his friends was not as funny as this concept. “The idea of this just made us laugh,” he says.

The real Kevin was a homebody, not a cat who looked longingly out the window, Wengert says, adding that he always felt bad for Kevin: “You could have been with Aubrey Plaza but you’re stuck with me in my studio apartment.”

In the series, Kevin soon lands at an animal rescue where he falls in with Cupcake (Whoopi Goldberg), a self-declared feral cat with a kinky and rebellious side; Armando (John Waters), an aristocratic cat with a haughty attitude; Judy (Aparna Nancherla), a cat with gross eye infections who is way more upbeat and hopeful about the world than she should be; and a shrill and bossy dog named Brandi (Amy Sedaris), who runs the human Seth (Gil Ozeri) — ostensibly the operator of the shelter.

A cartoon man takes a photo with a camera of a group of cats and dogs standing against a storefront window.

After his owners break up, Kevin decides to stay at an animal shelter, where he makes friends with a rag-tag group of cats, dogs and other animals.

(Courtesy of Prime)

“This idea of fending for yourself and trusting your instincts is part of checking off boxes to show you have lived a quote unquote real life,” says Schwartzman, briefly growing philosophical about what intrigued him about playing a neurotic cat.

The cats encounter plenty of other animals on their adventures, from a drunk spider to a deer that gets hit by a car and curses out the driver. “That made me laugh out loud,” says Plaza, who also voices numerous animals, including the spider and a pitbull love interest for Cupcake. “I’ve always wanted a love story with Whoopi Goldberg,” she adds.

(Wengert voices a parrot named Paco, among others, and says there’s talk of adding a tortoise.)

One secondary character is a horse named Patti Lupony, who, naturally, is voiced by Patti LuPone. She’s part of a stacked guest star roster that includes Addison Rae, Cary Elwes, Charles Melton, Nicole Byer, Jim O’Heir, Maria Bamford, Quinta Brunson and Tig Notaro. Many of the actors, including Schwartzman, Waters, LuPone and O’Heir, are Plaza’s friends.

“I like to do things that people don’t expect me to be in, and this is definitely one of them,” says Waters, adding that “Armando is not a real fan of humans, and as a human, I’m not a real fan of cats.”

Still, Waters, who prefers dogs, says he was easily able to get into Armando’s skin. “I’m a Method actor, so I was crawling around the floor,” he jokes, before adding, “If I was a cat, I would probably act like Armando.”

For what it’s worth, Schwartzman also owns dogs, though he’s quick to point out that growing up in Los Angeles, he volunteered at a cat shelter, and these days Plaza actually owns a dog, too. But as anyone who has seen her in “Parks and Recreation” or other roles would surmise, Plaza says, “I have cat-like tendencies and relate more to cats.”

Plaza and Wengert also incorporated the actors’ sensibilities and personalities.

“We would change things on the fly based on the actor’s input,” Wengert says.

Plaza says that Waters is known for being provocative and loves reading tabloids but that he asked to tone down Armando’s snide put-downs of celebrities. “I felt ill at ease about them,” Waters says. “I’ve gotten away with my career for 50 years because I’m not mean. My specialty is praising things other people hate, not the other way around.”

Wengert says the change “forced us to dig deeper and find something more unique in the character, so I’m happy that he asked us to make the change.”

(He adds that he expected Goldberg to object more “because we gave her so many outrageous lines” but she rarely did, except “to pitch something that was even funnier that worked better.”)

Plaza knew Kevin’s neuroses fit Schwartzman but also that he could bring his own touches while improvising. “He’s really funny about his own body,” she says. “We were hanging out once and he just said, ‘Feel this, my leg is really heavy.’ So we put that in for Kevin.”

Schwartzman says, seemingly seriously, “Wow, I don’t have a memory of that exact moment, but it is true that my leg does feel heavy.” And he adds that his friendship with Plaza enabled him to feel comfortable throwing out ideas during recording, adding that the improvising and tweaking went both ways, with the writers constantly adding new ideas. “It was a collaboration and an evolution,” he says.

The writers room is stacked with people who, like Plaza and Wengert, hail from the Upright Citizens Brigade improv world. (Wengert, who also imported writers he’d worked with on Netflix’s “Big Mouth,” was running the UCB school when they met.) “Our sense of humor is very aligned,” Plaza says.

While Plaza loves how “freeing” animation is — “your imagination can run totally wild” — she says that even though it’s out of character for her, she’d play the “bad cop” in the writers room. Wengert says one day she brought Schwartzman in and he and the writers pitched some wild ideas that made them say, “What the f— is going on.”

“We’re just building the world, so you need some rules, otherwise all the inanimate objects can start talking,” Plaza says. “When things started getting too crazy, I’d say, ‘Let’s rein it in.’”

The example Wengert gives is that they can briefly have a talking pizza slice (it is New York, after all) but they don’t want it to become close friends with Kevin in a major plotline.

But if they get to produce a second season — the scripts are already written — Plaza says the leash will get looser “and it will get more insane.”

Source link

Venezuela in talks with Siemens, GE over power crisis

Avilio Troconiz (C), regional president of the Primero Justicia party in Zulia, speaks at a press conference in front of the Las Tarabas electrical substation in Maracaibo, Zulia state, Venezuela, on March 26. The party denounced the the electricity crisis, which has worsened in recent months. Photo by Henry Chirinos/EPA

April 20 (UPI) — Venezuela’s interim president, Delcy Rodríguez, said her government is talking with two major companies to address the country’s power crisis, citing recent diplomatic engagement with the United States.

“Thanks to that diplomatic dialogue, I can say we are now in direct contact with Siemens and General Electric to resolve the electricity problem in Zulia state,” Rodríguez said Sunday during a public event broadcast by state television.

She said the government decided to “open a new chapter in national political life” and in Venezuela’s international relations following a Jan. 3 U>S> military operation that captured President Nicolás Maduro and his wife, Cilia Flores.

Analysts say Zulia, a key oil-producing region in western Venezuela, is critical to the country’s hydrocarbons industry. Persistent electricity shortages have limited efforts to boost crude production, making restoration of the power system a strategic priority for economic recovery.

Situated at the western edge of the national grid, Zulia is the last region to receive electricity transmitted from the south. Failures in the transmission network often leave it disconnected. The system in the region operates at less than 40% of installed capacity.

According to local outlet El Tequeño, both companies conducted technical missions in March to assess Venezuela’s electrical infrastructure and present rehabilitation proposals.

The inspections included hydroelectric facilities in the Bajo Caroní complex in Bolívar state, following a February visit to Caracas by U.S. Energy Secretary Chris Wright.

Rodríguez made the remarks at the launch of a 13-day pilgrimage she called to demand the full lifting of economic sanctions imposed on Venezuela.

“Enough sanctions against the noble Venezuelan people,” she said, addressing the governments of the United States and Europe, according to Globovisión. She added that economic freedom is a sovereign right, not a concession from foreign powers.

The mobilizations began in Zulia, Amazonas and Táchira states and were led by Rodríguez, National Assembly President Jorge Rodríguez and ruling party leader Diosdado Cabello.

International sanctions have worsened Venezuela’s electricity crisis by limiting access to financing and technology needed to maintain and upgrade infrastructure.

A partial easing of U.S. sanctions on the oil and mining sectors has opened the door to talks with companies such as Siemens and General Electric to address those gaps.

Source link

Iran expands limited internet access but restrictions remain for most | US-Israel war on Iran News

Tehran, Iran – Iranian authorities have been slowly expanding a list of individuals and entities deemed eligible to have limited internet access. However, the action serves only to illustrate that most of the population of more than 90 million people remains disconnected during the war with the United States and Israel.

The government imposed a near-total internet shutdown across Iran within hours of the first bombs falling in downtown Tehran on February 28. The move has seen internet connectivity reduced to about 2 percent of pre-war levels at most, according to monitors.

Recommended Stories

list of 3 itemsend of list

A limited intranet functions to keep some local services and apps alive, but people are highly frustrated, and the economy has suffered billions of dollars in lost revenue as a result of more than 1,200 hours of the digital blackout. One business, however, is thriving: the black market for internet connections.

This week, tens of thousands of people and organisations selected by the state based on their positions and professions signed up or received text message invitations to connect through a service called Internet Pro.

That is the name selected for a limited and metered internet connection through which thousands of sites and most global messaging services are blocked but some applications, app stores and Google services function.

The service is being sold in the form of 50-gigabyte data packages by three top state-linked telecommunications companies. State authorities can also issue limited internet protocols (IPs) for global connectivity to designated office spaces of approved companies and businesses.

Applicants need to provide full identification and professional or referral documents. Business owners and traders introduced to the Ministry of Information and Communications Technology and other authorities through their guilds and chambers of commerce were among the first to be connected this month.

Doctors, university professors, researchers and academics in various fields were nominated by the Ministry of Science this week. Freelancers were told to sign up through a webpage set up by the state-linked Iranian ICT Guild.

This is a separate service from that enjoyed by holders of “white SIM cards”, which offer less restricted connections and are reserved for officials, state-linked entities and individuals, journalists and some civilian supporters of the establishment perceived to be helping “get the message out” on behalf of the government.

A tiered system in action

For years, Iranian authorities have stressed that they are against a tiered internet system, which in effect renders connectivity a privilege, not a fundamental right in an age of rapid digital advancement.

But with such a system now in action and expanding, some state media are now framing it as a necessity despite harsh criticism regarding such an idea from the population over the years.

The state-linked ISNA news agency this week branded Internet Pro an “expert option providing a stable connection for professional activities”. The outlet encouraged potential applicants to contact the three telecommunications companies to see if they are eligible.

No such tiered system was implemented at a significant scale around the short-lived internet blackout imposed during the 12-day war with Israel in June or the 20-day near-total shutdown in January during deadly nationwide protests.

But the extended and unprecedented internet shutdown now in place sees eligible people and businesses giving in and electing to sign up.

Not all are convinced, however. Many are reported to have taken to state-run online platforms and news sites with demands for the full restoration of the internet.

On the local technology-focused site Zoomit, which can be reached through the intranet, thousands of people have recounted experiences of lost jobs and disrupted lives as a result of the shutdown.

“I’m a cybersecurity and network expert. Our servers and systems have not received security updates for about two months, and we’ve lost all our integration with open-sourced communities,” one user wrote. “This has significantly increased risks and stopped development, it’s unclear if my team will have its contract renewed this year in these economic conditions.”

Iranians circumventing the filternet through virtual private networks (VPNs) and other methods have also rejected the tiered system.

Aliasghar Honarmand, the editor in chief of an online privacy news website and an online medical news and research service, wrote on X that he has ignored multiple offers for Internet Pro over recent days.

“Access to the free internet is a fundamental and basic right for all people,” he wrote, adding that giving it to elites based on state classifications leads to normalising severe internet disruptions, creating an illusion of free connectivity, undermining social cohesion, violating personal privacy and propagating a black market.

Getting around the gatekeepers

Since the start of the war, Iranians going online from inside and outside the country have observed a battle between developers working on behalf of the state to deepen internet restrictions and those trying to skirt them.

This week, a circumvention method known as SNI (server name indication) Spoofing became popular after an unidentified user reported that he managed to establish a secure connection and published a guide.

The method tricked internet censors into thinking the users were visiting a permitted site or service when they were accessing blocked content. However, the authorities quickly moved to block gateways allowing the method to work, resulting in its demise within days.

Two experts who spoke with Al Jazeera said authorities are now deploying a heavily restrictive and centralised internet architecture through something called a national NAT (network address translation): a single country-scale gateway that all internet traffic must pass through.

This allows the authorities to reroute and bundle connectivity across Iran through a central operator with the aim of achieving higher levels of control and monitoring and an improved capacity to combat circumvention efforts.

But the method is hardware-intensive and costly, can lead to degraded or lagging connections and could potentially act as a single point of failure for saboteurs to exploit, the experts said.

One young resident of Tehran who has used Internet Pro issued for her university professor mother told Al Jazeera that most platforms considered essential by many people, such as Telegram, WhatsApp and Instagram, remain blocked on the service. ChatGPT was also blocked, but China’s DeepSeek was available on the service, she added.

“This is ridiculous and stupid because all groups of society, for whatever reason, need and deserve the internet. This move excludes most people who have no links to get them connected, including the elderly, and serves to keep the internet out for longer,” she said.

Source link

Jack Whitehall’s dad ‘absolutely mortified’ to discover he’s related to ITV legend

Jack Whitehall revealed his father’s true reaction to discovering a surprising connection to an ITV legend after spotting him at a funeral

Jack Whitehall has revealed his father, Michael Whitehall, was left “mortified” to discover their connection to antiques expert David Dickinson. Uncovered in an awkward circumstance – Jack recalled spotting the former Bargain Hunt at a family funeral.

Appearing on Alan Carr’s Life’s A Beach, the 37-year-old said of the surprising link: “You know I’m related to David Dickinson? This is my bizarre fact… not by blood, but he’s married to a cousin of my mum’s.

“We found this out because we went to a funeral and David Dickinson was stood on the other side of the grave,” he continued.

When quizzed about whether David’s famously bronzed complexion is as striking in person as it appears on television, Jack quipped that “he was glowing”.

He described the antiques expert as “more impressive up close,” before revealing how his father took the news of their family tie.

“My dad was absolutely mortified,” he recalled. “He was like, ‘We will never speak of this again’. And obviously, I now want to get it out there as much as I can, far and wide.”

David, 84, has been married to Lorne Lesley since 1968. The couple are understood to have first crossed paths in Manchester, and their romance blossomed from there.

They went on to welcome two children together, while he also adopted her son and daughter from an earlier relationship, Robert and Katrina.

Previously discussing their relationship, the Dickinson’s Real Deal star told The Mirror: “Lorne lets me think I’m the master of my own home. Any woman who knows what she’s doing lets her man think he’s in charge – but we know we’re not really.”

He also sang his wife’s praises, adding: “Lorne is half African and half Welsh and hails from Tiger Bay, just like Shirley Bassey.

“She’s very glamorous – a lovely, striking lady – and she has more talent in her little finger than I have in my whole body.

“When I met Lorne, I was working in the textile industry but ready for a change of career. As I got to know her better, we decided I should become her manager. Together we travelled the world, and it was during this time that my interest in antiques began to flourish,” he added.

Meanwhile, Jack married Roxy Horner his partner of six years at Euridge Manor, a 17th-century estate in the Cotswolds, last weekend.

The stunning venue, sprawled across 450 acres, boasts a boating lake, an orangery, a helicopter pad, a pergola draped in wisteria and a ballroom.

Reportedly costing £250,000, the couple’s ceremony was attended by a host of celebrity guests, including James Corden, Jamie Redknapp and Andrew ‘Freddie’ Flintoff.

Source link

Mother, 6 children die in Pennsylvania house explosion

A mother and her six children, ranging from 3- to 11-years-old, died in a fire in Clinton County, Pa., when their home exploded. File Photo by Bonnie Cash/UPI | License Photo

April 20 (UPI) — A mother and her six children, ranging from 3- to 11-years-old, died in a fire in Clinton County, Pa., when their home exploded.

On Sunday at about 8:42 a.m. EST., emergency response units from nearby Centre and Lycoming counties were alerted to a fire on Long Run Road in Lamar Township. The home of 34-year-old Sarah B. Stolzfus and her children was fully engulfed in flames when first responders arrived on the scene.

State police said the cause of the explosion is under investigation.

Stolzfus and her children, four boys ages 11, 10, 4 and 3, and two daughters, ages 8 and 6, were pronounced dead at the scene.

A propane leak inside the home is a potential cause for the explosion, state police said. There were propane tanks outside of the home that did not explode, nor were they involved in the fire.

Children race to push colored eggs across the grass during the annual Easter Egg Roll event on the South Lawn of the White House in Washington on April 21, 2025. Easter this year takes place on April 5. Photo by Samuel Corum/UPI | License Photo

Source link

‘Israel never talked me into the war with Iran,’ Trump says | US-Israel war on Iran News

Donald Trump has denied being dragged into war with Iran by Israel, as the United States president faces increasing criticism over the conflict, including from segments of his own base.

“Israel never talked me into the war with Iran, the results of Oct. 7th, added to my lifelong opinion that IRAN CAN NEVER HAVE A NUCLEAR WEAPON, did,” Trump wrote in a social media post on Monday.

Recommended Stories

list of 3 itemsend of list

There is no public evidence linking Iran directly to Hamas’s October 7, 2023 attack against Israel. Trump’s own intelligence chief Tulsi Gabbard also testified to Congress in March that Iran is not building a nuclear weapon.

For eight months prior to the war, Trump had been saying repeatedly that the June 2025 US strikes on Iranian facilities “obliterated” the country’s nuclear programme.

Many of Trump’s critics have argued that Iran did not pose an imminent threat to the US, and that the war only advances the interests of Israel at the expense of the safety and prosperity of Americans.

Iran responded to the joint US-Israeli strikes – which killed the country’s Supreme Leader Ali Khamenei, other top officials and hundreds of civilians on February 28 – by blocking the Strait of Hormuz, sending oil prices soaring.

In the US, energy costs have skyrocketed, fuelling inflation. The price of one gallon (3.8 liters) of petrol has remained over $4 – up from less than $3 before the war, more than a week after the truce between Washington and Tehran came into effect.

A recent poll by NBC News suggested that two-thirds of Americans disapprove of Trump’s handling of the war.

With dissatisfaction growing, many of the president’s critics have pointed to Israel as the real power behind the war – portraying Trump as a weak leader following Israeli Prime Minister Benjamin Netanyahu.

“He entered a war – got pulled into it by Bibi Netanyahu, let’s be clear about that – entered a war that the American people do not want,” Kamala Harris, Trump’s 2024 Democratic opponent, said last week.

Harris served as vice president in the Joe Biden administration, which provided diplomatic and military support for Israel’s genocidal war on Gaza for more than two years.

During the 2024 campaign, Trump presented himself as the “peace” candidate, promising to end wars that were started under the Biden administration.

Trump’s National Security Strategy, released last year, also said that Washington would pivot its foreign policy and military resources from the Middle East to the Western Hemisphere.

But Netanyahu, who has visited Trump in the US six times in one year, has continued to push for a hardline against Iran. The most vocal supporters of the war in Washington have also been Israel’s closest allies.

On Monday, Trump renewed his attacks on the mainstream media for its coverage of the war with Iran.

“I watch and read the FAKE NEWS Pundits and Polls in total disbelief. 90% of what they say are lies and made-up stories, and the polls are rigged, much as the 2020 Presidential Election was rigged,” the US president wrote.

He also touted his policies in Venezuela, where the country has remained stable and become more friendly to Washington after US forces abducted President Nicolas Maduro in January.

In Iran, however, the US-Israeli strikes led to the closure of Hormuz and sustained Iranian attacks across the region for nearly six weeks.

The conflict is now paused, and further talks between US and Iranian officials could take place in Pakistan this week. But both sides have threatened to renew the fighting if a deal is not reached.

“Just like the results in Venezuela, which the media doesn’t like talking about, the results in Iran will be amazing – And if Iran’s new leaders (Regime Change!) are smart, Iran can have a great and prosperous future!” Trump wrote.

Source link

Joe Lycett reveals hospital dash with 16 month old son as he gives rare insight into fatherhood

JOE Lycett has revealed he had to rush his 16-month-old son to hospital in a rare parenthood admission.

The comedian keeps his personal life notoriously private and shocked fans in 2024 when he revealed he had become a father, welcoming the little one with his long-term girlfriend.

Joe Lycett has revealed his 16-month-old son was rushed to hospital recently in a health scare Credit: YouTube/ Whats My Age Again Podcast
The comedian shares the little one with his partner Denise, with the couple keeping their family fiercely life private Credit: Instagram

Joe’s girlfriend, whom he refers to as ‘Denise’ to keep her real name private, remains out of the limelight, with their relationship very under the radar.

But appearing on Katherine Ryan’s What’s My Age Again Podcast, Joe spoke about his experience with fatherhood and detailed a recent health scare with the youngster.

Choosing not to share his name, Joe jokingly nicknamed his little one “the punisher”.

He explained: “The punisher was poorly recently, we had to go into hospital and whatever.”

Bikini snap

Katie Price shows off huge tattoos as she strips off to barely-there bikinis


FAN’S FURY

Ryan Thomas hits back after he’s accused of ‘being rude’ to ‘old lady’ fan

” I got a real sense of, ‘I would take any pain that you have, a thousand times over. I would bulldozer through a nursery to save you. I would do whatever it takes,” explained Joe of the unwavering love he has for the baby boy.

He later referenced the hospital incident again, confirming that the youngster had to be assessed in A&E.

Talking about how the family had a parking debacle during the hospital trip, he explained: “So, the punisher was ill. I drove to A&E, Birmingham children’s hospital.

“Parked up, took a picture of the Ringo number but didn’t do it straight away, like, ‘Oh, I’ll just wait while my son was unwell’, I thought, ‘I’ll do it in there’.

“So, he was being assessed and I was paying for parking whilst he was being assessed, so I had one eye on him and one eye on this,” said Joe, who continued to explain that he ended up getting a parking ticket for not doing so in time.

Joe also gave an insight into family life and his decision to become a parent as he said: “I always said I didn’t think I’d have kids but if one happened then I’d have a really good go at it.

“But then, I think, being in a stable, loving relationship, suddenly I was like, ‘Oh it would be fun to have a go at this’.

“Once we started talking about it, it became an inevitability.”

The comedian then touched on his decision to keep his family life, including his relationship, out of the public eye.

There are no family snaps on his social media, with his son and partner not featured anywhere online in connection to Joe.

Explaining the reason behind this, Joe said: “For the punisher, it’s up to him if he wants to do that later and be in the public eye.

“Because there is an inherit risk in being in the public eye, being known, having your face known and all of that.

“And if I end up doing something appalling he can change his surname and no one knows who he is, essentially.

“And then with Denise she just has a job where she works with vulnerable people.

“So if people know that I’m with her then it might affect her work. And also she has no desire to be in it – it’s weird to do what we do. “

In the rare admission, Joe detailed family life and how it has changed him as a person Credit: YouTube/ Whats My Age Again Podcast
Despite Joe’s outgoing nature and tendency to pull wild stunts, he explained that when it comes to family, he wants them to remain out of the limelight Credit: Rex

Source link

Bulgaria’s former President Radev wins election: All you need to know | Elections News

Bulgaria’s eighth parliamentary election in five years has concluded with former president Rumen Radev’s Progressive Bulgaria party emerging as the clear winner. Radev will be the next prime minister.

While pollsters predicted a win for Radev ahead of the election, they did not necessarily expect it to be such a large one.

Recommended Stories

list of 3 itemsend of list

With 98.3 percent of ballots tallied on Monday, official figures show Radev’s party taking 44.7 percent of the vote, and likely to secure roughly 130 of the 240 seats in parliament. The centre-left party has come in far ahead of rivals, raising hopes among voters for a more stable government after years of fragile coalitions and repeated votes.

However, questions remain over what Radev’s foreign policy will entail and what his election means for Bulgaria’s position within the European Union and NATO.

Here is what you need to know:

Who is Rumen Radev?

The 62-year-old served as Bulgaria’s president for nearly a decade before stepping down in January this year to launch his bid to become prime minister.

The former air force commander has positioned himself as an outsider, saying he wants to rid the country of its “oligarchic governance model”, amid widespread frustration with corruption and political turmoil that has gripped the country of 6.6 million people.

In 2025, Radev supported anti-corruption protests that brought down the conservative-backed government of former Prime Minister Rosen Zhelyazkov. He urged voters to turn out in large numbers to counter vote-buying.

At a pre-election rally on Wednesday last week, he pledged to “remove the corrupt, oligarchic model of governance from political power”.

epa12899730 Rumen Radev, leader of the Progressive Bulgaria (PB) coalition, casts his ballot during the parliamentary elections in Sofia, Bulgaria, 19 April 2026. Approximately 6.6 million voters are heading to the polls to elect 240 members of the National Assembly in an attempt to establish a stable coalition government following a period of prolonged political deadlock in the Balkan nation. EPA/BORISLAV TROSHEV
Rumen Radev, leader of the Progressive Bulgaria (PB) coalition, casts his ballot during the parliamentary elections in Sofia, Bulgaria [Borislav Troshev/EPA]

Radev’s stance on foreign policy has drawn attention in Europe, however.

Although he publicly condemned Russia’s 2022 invasion of Ukraine, he has also opposed providing military support to Ukraine and called, instead, for renewed, “practical relations with Russia based on mutual respect and equal treatment”.

Radev objected to a 10-year defence pact concluded between Bulgaria and Ukraine in March.

He has also called for the resumption of Russian imports to Europe, despite EU sanctions on Russian oil and a decision at the end of last year to cease all energy imports from Russia by 2027.

All this has led to critics labelling him “pro-Russian”. Radev, however, says he is merely taking a pragmatic approach.

“We are the only member state of the European Union that is both Slavic and Eastern Orthodox,” he said in an interview with Bulgarian journalist Martin Karbovski.

“We can be ‌a very important ⁠link in this whole mechanism … to restore relations with Russia,” he added.

Following the election, Russia congratulated Radev, welcoming his victory.

“Of course, we are impressed by the statements made by Mr Radev, who won the election, and by some other European leaders regarding their willingness to resolve problems through pragmatic dialogue,” said Kremlin spokesman Dmitry Peskov on Monday.

On Europe, some label Radev a eurosceptic, as he has criticised aspects of EU policy, including reliance on renewable energy and Bulgaria’s adoption of the euro.

At his campaign rally on Wednesday last week, he said: “The coalition-makers introduced the euro in Bulgaria without asking you. And now, when you pay your bills, always remember which politicians promised you that you would be in the ‘club of the rich’.”

Following his victory, he told reporters: “A strong Bulgaria and a strong Europe need critical thinking and pragmatism. Europe has fallen victim to its own ambition to be a moral leader in a world with new rules.”

Nevertheless, Radev has signalled his willingness to cooperate with pro-European parties on issues like judicial reform and has stated that Bulgaria will “continue on its European path”.

Following his win, European Commission President Ursula von der Leyen said: “Bulgaria is a proud member of the European family and plays an important role in tackling our common challenges.”

How significant is this result?

Since 2021, Bulgaria has been through multiple governments, many brought down by protests or parliamentary disagreements.

The election result places Radev’s party, with 44 percent of the vote, well ahead of the centre-right GERB party of former Prime Minister Boyko Borissov, which secured 13.4 percent of the vote, and the reformist PP-DB coalition, with 12.7 percent.

The margin between the parties is wider than pollsters predicted. On Friday last week, according to Bulgaria’s Alpha Research, Radev’s Progressive Bulgaria was projected to win, but with only 34.2 percent of the vote, followed by Borissov’s GERB-UDF with 19.5 percent. This led observers to predict that a coalition government would be necessary.

Despite securing a clear majority, however, Radev has yet to rule out creating a coalition with a smaller party to form a government.

“We are ready to consider different options so that Bulgaria can have a regular and stable government,” he told reporters on Sunday.

This latest election was called after former PM Zhelyazkov announced in December that his cabinet would resign, amid a looming no-confidence vote.

The election campaign centred heavily on cost-of-living pressures, corruption, and other economic concerns, with many voters expressing frustration at the lack of credible political alternatives.

What will Radev’s role as prime minister be?

Although Radev is best known for holding the title of president, that is a largely ceremonial role in Bulgaria’s political system.

The president serves as head of state, representing national unity and playing a role in foreign policy; executive power lies primarily with the prime minister and his cabinet.

The prime minister appoints his cabinet ministers, sets the government agenda, and is the key representative of Bulgaria in international affairs, including within organisations like the European Union and NATO.

The prime minister remains in office unless he chooses to resign or is removed in a no-confidence motion.

Source link

Carrier Tracker As of April 20, 2026

Here’s TWZ’s weekly carrier tracker monitoring America’s flattop fleet, including deployed Carrier Strike Groups (CSG) and Amphibious Ready Groups (ARG), using publicly available open-source information.

The Gerald R. Ford CSG transited the Suez Canal southbound on April 16, the Associated Press reported on Friday, once again entering the Red Sea and U.S. Central Command (CENTCOM) area of responsibility (AOR). The second CSG in the region, led by USS Abraham Lincoln, is operating in the northern Arabian Sea, enforcing the naval blockade of Iranian ports and coastal areas. The George H.W. Bush CSG is reportedly transiting around the Horn of Africa en route to the Middle East, according to USNI News, but TWZ has been unable to independently confirm via open sources. Following the arrival of USS George H.W. Bush, the U.S. will have three carriers positioned in the Middle East should the ceasefire fail and combat operations resume.

The Tripoli ARG is also supporting blockade measures, with the embarked 31st Marine Expeditionary Unit (MEU) boarding and seizing Iranian-flagged M/V Touska on April 19 after USS Spruance fired multiple 5-inch rounds, targeting the engine room and disabling the vessel’s propulsion. “American forces issued multiple warnings and informed the Iranian-flagged vessel it was in violation of the U.S. blockade. After Touska’s crew failed to comply with repeated warnings over a six-hour period, Spruance directed the vessel to evacuate its engine room.” The second ARG-MEU tasked to CENTCOM, the Boxer ARG-11th MEU, is currently transiting through U.S. Indo-Pacific Command at an undisclosed location.

At a press conference on Thursday, Chairman of the Joint Chiefs General Dan Caine and CENTCOM Commander Admiral Brad Cooper provided a detailed briefing on the opening hours of the blockade, which TWZ covered here, and shared unclassified slides of ship positions before and after implementation. Below is an animation visualizing the first 48 hours of the U.S. blockade, and confirmed Navy ships operating in the Arabian Sea and Indian Ocean at the time.

“Since the blockade’s commencement, U.S. forces have directed 25 commercial vessels to turn around or return to an Iranian port,” CENTCOM said in the release. “In addition to this blockade, the joint force, through operations and activities in other areas of responsibility, like the Pacific Area of Responsibility, under the command of Admiral Paparo, will actively pursue any Iranian-flagged vessel or any vessel attempting to provide material support to Iran,” Gen. Caine added.

Back stateside, the Theodore Roosevelt CSG departed San Diego on April 15, according to local ship spotters. A U.S. 3rd Fleet spokesperson told TWZ the CSG is underway conducting routine operations and integrated training in the 3rd Fleet AOR and “remains ready to respond to crisis or contingency at any time.” Elements of the group were recently outfitted with a new Raytheon Coyote counter-UAS 8-cell launcher, which could be tested during upcoming training periods.

Note: Positions are general approximations. Non-deployed LHA/LHD amphibious warships are not shown.

Contact the author: ian.ellis-jones@teamrecurrent.io

Source link

Punk in the Park festival’s founder donated to Trump. The fans revolted

Cameron Collins was sick of Joe Biden.

The owner of concert promoter Brew Ha Ha Productions describes himself as a libertarian-leaning conservative who built his career in San Juan Capistrano. He’d kept his personal politics out of his popular SoCal events, like the ska fest OC Super Show and the nationally touring Punk in the Park fest, a staple for bands like Bad Religion and Pennywise.

On May 30, 2024, Collins felt dismayed that Biden had pursued reelection. In a fit of anger, he donated $225 to Donald Trump’s campaign.

“It was just an impulsive thing,” Collins said in an interview. “Biden had said he was going to run again. I was like, nope. He’d said he wasn’t. It was more about that than anything. I don’t post anything political or talk about anything politically. I’ve never donated to anything like that before.”

That donation proved fateful. After a small punk label discovered and decried Collins’ donation, the scene turned on him. Influential bands pulled out of his festivals or said they wouldn’t return.

On Feb. 27, Collins canceled every Punk in the Park date for 2026.

“The current climate surrounding the events has created challenges that make it impossible for us to move forward,” the organizers wrote on Instagram.

It’s no surprise that an underground music scene would loathe a Trump-donating promoter. Amid the Iran war, raids by U.S. Immigration and Customs Enforcement, and the Epstein files, many Americans want Trump supporters gone from their lives, some viewing any form of support for him as an attack on their and others’ safety and dignity.

Yet until this donation, Collins was a respected promoter whose events sustained hundreds of acts, including progressive bands. Some artists who relied on Collins’ festivals — even if they hate his politics — said the backlash will hurt their livelihoods too.

“It was the worst money I ever spent,” Collins said. “It was not worth this.”

On a March afternoon after canceling his tours, Collins spoke to The Times on a Zoom from his home in Texas. He wore a thick gray beard and the chunky glasses of an aging rocker. His home office was plastered in concert posters from his decades of shows, which include Punk in Drublic (a long-running collaboration with his friends in the left-leaning band NOFX), Silverado Showdown in Orange County and SoCal rock radio station KLOS’ Sabroso Festival.

He expressed bewilderment over the fan revolt that turned him from a scene mogul who gave to pediatric cancer research charities to a villain with a gutted festival business.

“I feel like my reputation with every artist I ever worked with was that they would say, ‘The guy’s got integrity. He treats everyone right. He fights for this scene,’ ” Collins said. “I’m wondering what is happening right now that this has become so polarizing.”

Asked what Trump policies he supported, Collins sighed and said, “A vote for a candidate is not an endorsement of everything they stand for. I am very antiwar. There were promises that Trump made — no more foreign wars, supporting Ukraine by ending that war, lowering prices on gas and on groceries. Dinner table topics.”

Those goals are significantly at odds with the president’s track record. Did Trump deliver on Collins’ donation?

“The way that this whole fiasco has gone down — no one would have voted for that,” he said.

Punk has long struggled with a reactionary streak. British bands in the ‘70s wore swastika armbands for shock value. The Sex Pistols’ Johnny Rotten and the Ramones’ Johnny Ramone turned rightward, and Orange County’s hardcore scene has had neo-Nazi extremists. Gen X punk fans who consider themselves anti-establishment might see online leftists as imposing on their ability to have consequence-free political speech.

Yet the vitality of today’s punk scene is driven by young, racially and sexuality-diverse fans who believe they are in grave danger from Trump’s policies.

Last year, Brandon Lewis, the founder of the Columbus, Ohio-based label Punkerton Records, was poking around on the donor database Open Secrets. He was curious how his scene was donating, and he’d attended Brew Ha Ha events like the Ohio punk festival Camp Anarchy. He checked where Collins put his money and was appalled that it went to Trump.

“We refuse to support, defend, or stay silent about someone who gave money to a man actively destroying everything we care about, deporting our friends and families, erasing the existence of our trans community, stripping away civil liberties, civil rights, and workers’ rights, while dismantling the Constitution itself,” Lewis wrote from Punkerton’s Instagram.

“I’m a combat veteran, and this administration is just pushing everything I believe in about freedom out the window,” Lewis told The Times. “When I would listen to Trump’s rhetoric about ICE — I’ve got friends who are undocumented. Supporting that in a financial way, supporting someone saying my trans friends don’t exist, and to do so coming from a music scene that to me is accepting and kind and certainly not ripping families apart, I couldn’t in good conscience let that go.”

Other bands in the scene, like Dillinger Four, found more donations — around $100 or $200 each — from Collins going to the Trump-supporting political action committees WinRed and Never Surrender and the Trump National Committee. Collins’ support ran deeper than a one-off gesture.

Left-leaning fans demanded that bands drop off Collins’ festival bills.

Dropkick Murphys, a rough-and-ready enemy of Trumpism in punk, had played Collins’ past events. When word of his donations spread, the band came out swinging.

“Punk Rock and Donald Trump just don’t belong together,” they wrote in an Instagram post . “So, upon finding out that Brew Ha Ha promotions donated to the Trump campaign, we will not be playing any more Punk in the Park shows.”

Some acts, like old-guard punks the Adicts and ska group the Aquabats, canceled sets at Collins’ events. Other bands, like Dead Kennedys, said they opposed his beliefs but fulfilled their contracts.

“Dead Kennedys have always stood firmly against authoritarianism, racism, and fascism. That has not changed,” the group wroteon social media. “After these scheduled appearances, we will not be participating in future Punk In the Park events.”

Collins said he understood why bands jumped ship. “There was so much pressure building,” he said. “The bands are a business. You have to say, at what level is the pay worth the headache?”

Yet he insisted that “anyone that pulled off did not pull out because they were standing for something, but were being pummeled to the ground by everyone that said they’d better do it or else. I don’t want those bands to go through that.”

Many fans say that Collins is seeing the predictable consequences of supporting a politician the scene despises.

Others struggled with what to do in response. Monique Powell, the singer for the Orange County ska band Save Ferris, describes herself as a “queer anarchist anti-Netanyahu Jewish child of a North African immigrant,” and far from a Trump sympathizer. Yet Save Ferris played Collins’ OC Super Show event in spite of the protests and bands pulling out.

She said that, while she opposes MAGA, she “wasn’t willing to disappoint fans and put hundreds of people out of work just because someone had a view I didn’t agree with.”

She said Collins “has been an important part of creating and nurturing this scene. He gave a lot of people work. From onstage, I see all the vendors, the stage crew, all providing jobs for people of all backgrounds. He’s given a place for fans to come together, even if they don’t all believe the same stuff.”

Save Ferris was a breakout act in the ‘90s and is now a working-class band on the ska and punk festival circuit. “I see the midsized, hometown venues that the bands of my ilk play — they’re being bought out or dying,” Powell said. “I’m not about to start getting out pitchforks for someone who did something that’s nothing compared to the effects of larger companies.”

Take, for example, Beverly Hills-based concert giant Live Nation, which was in the news last week after a federal jury in New York ruled against it in an antitrust case. Live Nation’s chief executive, Michael Rapino, has donated to Democrats Kamala Harris, Sens. Jacky Rosen of Nevada, Lisa Blunt Rochester of Delaware and Adam Schiff of California, and the music biz-friendly Texas Republican John Cornyn. Live Nation’s PAC has given to Republican Sens. Marsha Blackburn of Tennessee and Ohio Rep. Jim Jordan, alongside several Democrats. Billionaire Philip Anschutz, whose namesake firm AEG is the parent company of Coachella promoter Goldenvoice, has donated millions to Republican politicians, PACs and party organizations for decades — exponentially more than Collins ever did.

It’s fair for to wonder why music fans who hold the line on supporting a Trump donor like Collins might attend those other shows. Lewis said he struggles with that contradiction too but said it hurt worse coming from a punk promoter.

“Donating to Trump is antithesis of what punk means. Hating people for their sexuality or skin color is not punk in the least bit. People clearly expected better from a punk rock festival,” he said.

“I think Live Nation should be broken in half,” Lewis added. “But it’s no knock on someone who wants to see Social Distortion at a Live Nation venue; they need escape as well. I’m just not going to pretend Live Nation is a beacon for good things.”

Those punk communities are pushing back beyond Collins’ events. The SoCal gothic-cumbia DJ collective Los Goths pulled out of the Orange County festival Los Darks after learning its organizers, Peachtree Entertainment, produced the MAGA-champion Kid Rock’s controversial Rock the Country festival. The Los Angeles crust-punk event C.Y. Fest was scrapped after its organizer, Ignacio “Nacho Corrupted” Rodriguera was accused of sexual misconduct (he called the claims “false allegations and misinformation,” but stepped back from the festival).

Collins’ company produces events outside the punk scene, focused on craft beer and other music genres. He recently revamped his upcoming Me Gusta festival into Sublime Fest after the rap group Cypress Hill pulled out. (Last year, Sublime played at the Trump National Doral golf course for the Saudi-backed LIV Golf tour.)

Collins is not sure how he’ll find his way back into the punk scene or if the fans will want him there again.

“I still go out into the audience because I just want to see, is it real? Do people hate me?” he said. “We have bands up there like the Casualties, who are flying [anti-ICE] flags. People are like, ‘You’re a fascist,’ but I’m paying a band to go on my stage to say whatever they want, and then signing a check and going, ‘Thanks for doing it.’ ”

In America‘s current political climate, left-leaning punk fans may not have patience for Trump sympathizers. Having heterodox beliefs is one thing; financially supporting the president is another. Collins is a free market guy, and the punk market has spoken.

Yet huge companies that donate to Trump and his allies are consolidating the industry. It’s harder for progressive punks who want the scene to reflect their values.

“I feel like we created a sustainable, realistic scene that can keep going for years, and bands can earn the money that they need to anchor those tours,” Collins said. His donation caused this avoidable backlash, but “if you take away festivals that are their anchors, like we have been for so many of these artists over the years, how do they tour? This is what the bands are telling me, that ‘we’re the ones getting killed here.’ ”



Source link

ALA releases list of ‘Top 11 Most Challenged Books List of 2025’

April 20 (UPI) — The American Library Association released its list of the “Top 11 Most Challenged Books List of 2025,” including titles by John Green and Sarah J. Maas.

The list, part of the 2026 State of America’s Libraries Report, is based on data from the ALA’s Office for Intellectual Freedom, which tracked 4,235 unique titles challenged across 2025. The number was the second-highest ever documented by the ALA, after 4,240 books were challenged in 2023.

The 2025 challenges included 713 attempts to censor library materials and services through access restrictions, including 487 books.

The most challenged book of 2025 was Sold by Patricia McCormick, followed by The Perks of Being a Wallflower by Stephen Chbosky, Gender Queer: A Memoir by Maia Kobabe, and Empire of Storms by Sarah J. Maas.

There was a tie for fifth place between Last Night at the Telegraph Club by Malinda Lo and Tricks by Ellen Hopkins.

The seventh book on the list was A Court of Thorns and Roses by Sarah J. Maas, followed by a four-way tie between A Clockwork Orange by Anthony Burgess, Identical by Ellen Hopkins, Looking for Alaska by John Green and Storm and Fury by Jennifer L. Armentrout.

The challenged titles of 2025 included 1,671 representing the lived experience of LGBTQ people and people of color — about 40% of the total challenges.

The report was released to coincide with National Library Week

“Libraries exist to make space for every story and every lived experience,” ALA President Sam Helmick said in a news release. “As we celebrate National Library Week, we reaffirm that libraries are places for knowledge, for access, and for all.”

The ALA said less than 3% of the challenges came from individual parents, with 92 percent of the challenges coming from government officials and political pressure groups.

“In 2025, book bans were not sparked by concerned parents, and they were not the result of local grassroots efforts,” said Sarah Lamdan, executive director of ALA’s Office for Intellectual Freedom. “They were part of a well-funded, politically-driven campaign to suppress the stories and lived experiences of LGBTQIA+ and BIPOC individuals and communities.”

A total 5,668 books were banned from American libraries in 2025, and 920 others were censored through access restrictions.

Children race to push colored eggs across the grass during the annual Easter Egg Roll event on the South Lawn of the White House in Washington on April 21, 2025. Easter this year takes place on April 5. Photo by Samuel Corum/UPI | License Photo

Source link