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May 21 (UPI) — Americans traveling back to the United States who have recently been in Democratic Republic of the Congo, Uganda or South Sudan will be required to enter the country through Washington, D.C.

Citizens and lawful permanent residents who have been in any of the countries in the last 21 days will be required to fly to Washington Dulles International Airport for enhanced health screenings before continuing on to their final destination, the U.S. Department of State announced.

The announcement follows an Air France flight bound for the United States on Wednesday afternoon being redirected to Montreal Trudeau International Airport after a passenger on board was determined to be from the DRC.

The U.S. Centers for Disease Control and Prevention on Monday already had blocked non-U.S. passport holders from entering the United States if they had been to any of the three African nations in the last 21 days.

An American doctor, one of several exposed in the DRC, was also confirmed to be infected with the Bundibugyo strain of Ebola on Tuesday and flown to Germany for treatment.

“The Dulles requirement applies to all passengers, including U.S. citizens and lawful permanent residents, who were present in those countries,” the State Department said in a travel advisory.

“Please be prepared for flight changes or cancellations,” the department said.

World Health Organization Director-General Tedros Adhanom Ghebreyesus said during a press conference that there have 51 confirmed cases of Ebola among the three countries, with nearly 600 suspected cases and 139 suspected deaths.

Tedros said the scale of the epidemic is “much larger” in the DRC, and that there have been deaths reported among health care workers, which suggests health care-associated transmission.

The U.S. Centers for Disease Control and Prevention has reported that the doctor whose case was confirmed this week, with officials flying him to Germany because of their previous experience in handling Ebola cases.

Although contacts linked to the doctor also have been moved to Germany and Czechia for observation, there have been no additional cases in Americans, the CDC said.

May 18 (UPI) — The U.S. Centers for Disease Control and Prevention on Monday restricted non-U.S. passport holders from entering the United States if they have been in Uganda, the Democratic Republic of the Congo or South Sudan in the past 21 days.

The agency made the announcement as there have at least 346 cases and 88 deaths in the DRC, on top of several cases that have been confirmed in nearby nations in people who been there, the CDC said over the weekend.

The CDC said that is coordinating with various agencies and companies to manage travelers who have been exposed to Ebola as it also deploys employees to support containment of the outbreak in the three nations.

“CDC assess the immediate risk to the general U.S. public as low, but we will continue to evaluate the evolving situation and may adjust public health measures as additional information becomes available,” the agency said in a situation summary.

In the last five days, the World Health Organization confirmed that the Ebola virus circulating in the three countries right now is the Bundibuyo virus, one of four known strains that have affected humans since Ebola was discovered in mid-1970s.

Although there is an approved, licensed vaccine against Ebola which has successfully been used to quell outbreaks, the vaccine — called Ervebo — only protects against acquisition of the Zaire species of Ebola virus, making it useless in the current outbreak, according to the CDC.

WHO on Saturday declared the outbreak a public health emergency of international concern.

In its update, WHO said that there are “significant uncertainties to the true number of infected persons and geographic spread associated with this event at the present time. In addition, there is limited understanding of the epidemiologic links with known or suspected cases.”

Ebola spreads from wild animals to humans and from human to human through direct contact with blood or other bodily fluids from infected individuals, and carries a case fatality rate of roughly 50%.

A number of affected Americans have reportedly been exposed to the virus during the outbreak.

The CDC has recommended that people who have traveled through the two countries in the last 21 days should immediately seek medical attention if they develop Ebola symptoms, which can include fever, weakness, vomiting, diarrhea or unexplained bleeding.

In addition to roughly 30 CDC employees dispatched to the region, and will join officials from several other global and regional health agencies, the WHO is expected to convene an emergency committee to advise the agency’s director-general on its response the outbreak.