The European Medicines Agency’s Committee for Medicinal Products for Human Use issued a positive opinion for Rasonque (daraxonrasib) as a second-line monotherapy treatment for adults with metastatic pancreatic adenocarcinoma.
The positive opinion was supported by data from the phase 3 RASolute
Far-right and far-left parties gain ground in local elections as Merz’s approval rating sinks.
Published On 7 Oct 20267 Oct 2026
Chancellor Friedrich Merz has hit out at what he called political “extremism” in Germany after recent stinging defeats in local elections to far-right and far-left parties.
“This is a task for our society as a whole, and it is one I intend to play my part in,” he said on Wednesday at an event in Berlin.
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Merz said “extremism” was forcefully making its way into the country’s parliaments, a day after a member of the far-right Alternative for Germany (AfD) was elected president of the state parliament in Saxony-Anhalt and the Left Party won out in Berlin’s state election last month.
“Anyone who casts their vote for the AfD is playing the extremists’ game and undermining credibility,” Merz said. “In any case, this is incompatible with the values of my party, the CDU [Christian Democratic Union of Germany].”
Despite winning the vote in the September 6 election in Saxony-Anhalt, the AfD fell three seats short of the absolute majority it had had sought. AfD lawmaker Tobias Rausch won the presidency of the parliament in the eastern German state Tuesday, backed by the left-populists in a secret ballot.
Founded in 2013 as a Eurosceptic movement, the AfD won over voters with an increasingly hardline opposition to immigration after about a million people fled to Germany in 2015, many of them from war-torn Syria.
The party has since become a dominant political force in much of eastern Germany, especially among voters disillusioned with mainstream parties, though most traditional parties have pledged not to enter coalitions with the AfD.
German Chancellor Friedrich Merz arrives for the weekly cabinet meeting in Berlin on October 7, 2026 [Tobias Schwarz/AFP]
Berlin election
Merz’s comments followed the far-left Left Party’s victory in the Berlin state election on September 20, in another defeat for the chancellor’s ruling Christian Democrats.
Lead candidate Elif Eralp campaigned on the soaring cost of housing in the German capital and immediately promised to follow through with a pledge to nationalise private housing associations that account for a large share of the city’s housing stock.
The result, which roughly doubled the party’s previous score, could see her become the first mayor of Berlin from the Left Party, which grew out of the former East German communist party following the reunification of the country 36 years ago.
Eralp, the 45-year-old daughter of left-wing Turkish parents who fled a coup in 1980, said the increasingly difficult rental situation was the biggest social problem in the capital.
She promised to proceed with nationalising the housing associations she said drove property speculation, in accordance with a referendum from 2021 in which 58 percent of voters backed a proposal to promulgate the move.
While the AfD has attracted most attention, the Left Party has also benefitted from a general turn against the mainstream centre-left and centre-right parties.
Meanwhile, Merz has received a record low approval rating. Earlier this month, a survey by Germany’s public broadcaster ARD found that only one in 10 respondents were satisfied or very satisfied with his performance, the lowest figure for any chancellor since the survey began in 1997.
Another major election test will come in North Rhine-Westphalia, Germany’s most populous state, where voters are set to elect a new parliament in April.
The vote marks the first time the far-right party gained enough seats to form its own caucus.
Published On 28 Sep 202628 Sep 2026
France’s far-right National Rally (RN) party and its allies have secured a record 14 seats in the Senate, effectively quadrupling its number in the 348-seat chamber just months before a presidential election.
Sunday’s indirect election of senators marked the first time Marine Le Pen’s party won enough seats to form its own caucus.
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“The results have exceeded our expectations,” Le Pen, the party’s leader and presidential candidate, said in a post on X.
“This is a historic victory, and a major milestone with the formation for the first time of a group in the Senate.”
RN entered the Senate for the first time with two seats in 2014, when it was known as the National Front, and won three seats in 2023.
It emerged as the single largest party in the lower-house National Assembly after President Emmanuel Macron called snap polls in 2024, though it fell well short of a majority.
Le Pen is preparing to run in next year’s presidential election when centrist Macron steps down.
RN president Jordan Bardella said the party’s senators would form an alliance with the Union of the Right for the Republic (UDR).
The right, centre and left-wing Socialists looked set to remain the three major forces in the upper house, according to initial results.
Saudi Arabia has intensified air strikes against Houthi positions in Yemen as the Iran backed group expands its territorial gains along the Red Sea coast, opening a new front in the wider Middle East war and adding pressure to already disrupted global energy supplies.
The Houthis have swept through several Yemeni towns and seized islands near the Bab el Mandeb Strait, a strategically important maritime route connecting the Red Sea with the Gulf of Aden. The group has also released footage showing its fighters capturing armoured vehicles from Saudi backed forces.
Houthi military spokesman Yahya Saree claimed that the group had shot down a Saudi F 15 fighter jet and said Saudi Arabia had conducted as many as 450 air strikes in Yemen during the week. Saudi authorities have not confirmed the aircraft claim, while officials supporting the internationally recognised Yemeni government have acknowledged that Saudi and allied forces are carrying out strikes against Houthi positions.
Saudi Arabia faces growing security pressure
The escalation has brought the conflict closer to Saudi territory. The Houthis have repeatedly launched attacks toward Saudi Arabia over the past week, prompting alarms in cities across the kingdom’s south and west.
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Saudi Arabia said its air defenses intercepted a Houthi drone south of Mecca before it entered restricted airspace over the holy city. Riyadh described the incident as a serious escalation because of the threat to religious sites. The Houthis denied targeting Mecca and accused Saudi Arabia of using the incident for propaganda.
The United States has also tightened its travel warning for Saudi Arabia, barring government employees from travelling within 20 miles of the Yemen border.
The latest escalation marks a sharp deterioration after several years in which the Saudi led conflict in Yemen had largely quietened under a ceasefire. The Houthis declared a naval blockade against Saudi Arabia in July and resumed attacks on areas in the kingdom before making rapid gains against forces aligned with the Saudi backed Yemeni government.
Energy markets face another shock
The renewed fighting is particularly significant because global energy markets are already under pressure from disruptions caused by the wider war involving Iran.
An attack blamed on Iran aligned fighters in Iraq last week knocked out Saudi Arabia’s East West Pipeline, an important route that allows the kingdom to move oil without relying entirely on the Strait of Hormuz.
Traders estimate that a prolonged closure of the pipeline could affect as much as 4% of global oil supply. Saudi Arabia has not given a timetable for restoring operations, although U.S. Energy Secretary Chris Wright said oil should begin flowing through the pipeline within days.
Brent crude was trading around $108 a barrel on Wednesday, close to its highest level since May. The average U.S. retail diesel price also reached a record above $6.30 a gallon.
The simultaneous disruption around the Strait of Hormuz and Saudi Arabia’s alternative export infrastructure increases the vulnerability of global energy markets to further regional escalation.
Washington faces another difficult choice
The developments also create a new challenge for the United States.
Saudi Crown Prince Mohammed bin Salman spoke with President Donald Trump last week seeking additional military support. So far, U.S. assistance has been limited to intelligence support.
The United States previously conducted a two month bombing campaign against the Houthis in 2025 before Trump announced a ceasefire with the group.
Washington now faces competing pressures. Greater support for Saudi Arabia could help contain the Houthi advance and protect regional energy infrastructure, but deeper military involvement could also expand the U.S. role in another theatre of the Middle East war.
What’s next
The immediate concern is whether the Houthi advance can be contained before the fighting causes further disruption to Saudi energy infrastructure and shipping routes.
For Saudi Arabia, the challenge is to push back against the Houthis while preventing the conflict from developing into a broader regional confrontation.
For global markets, the key issue will be whether disruptions to Saudi oil infrastructure remain temporary. Continued attacks on energy facilities or shipping routes could place additional pressure on already strained supplies.
The developments in Yemen therefore carry consequences well beyond the country’s existing conflict. The combination of Houthi territorial gains, pressure on Saudi Arabia and disruption to major energy routes has created another potential source of instability for the global oil market.