Brain

EXCLUSIVE: After Sarah-Jane Doherty found out she had a brain tumour the size of a golf ball in her brain, she got in touch with loveholidays to cancel a £1,100 upcoming trip – but claims they initially ‘didn’t want to know’

A young woman who is awaiting brain surgery for a tumour the size of a golf ball watched her mum sob while fighting for her holiday to be refunded after being told she was unfit to fly. Sarah-Jane Doherty, 24, from Doncaster in Yorkshire, was told she had a brain tumour in June 2026 after one year of being misdiagnosed.

She first noticed she was ill in July 2025 when she found herself being overly exhausted, to the point where she could not stand up for long periods of time. Other symptoms included depressive episodes, psychosis, hallucinations, manic episodes, and issues with her mood being up and down, which led professionals to believe she was displaying symptoms of bipolar disorder.

This meant she was put onto anti-psychotic medications which masked what would have been one of her major symptoms, seizures, as an electric shock-type of feeling down her left side. She also suffered issues with her vision before being rushed to A&E after having a severe headache that caused her so much pain that she sobbed on her bed.

After having a CT scan at Doncaster Royal Infirmary, Sarah-Jane was told doctors thought she had a bleed on her brain, and that she would need to be admitted and have an MRI scan. The next morning, Sarah-Jane’s life changed forever after being told she had a brain tumour around the size of a golf ball.

Medication masked a golf ball-sized brain tumour

She said: “They told me in a bay of four people by myself that I had a brain tumour, and that they think is a glioma. I was just distraught, I was absolutely hysterical.

“I rang my mum straight away, and she came into the hospital. She rang my dad and he came home from work to see me. I feel a bit like I’m in an episode of Grey’s Anatomy, like it just doesn’t feel like it’s actually me.

“I was upset, I was stressed thinking, ‘what if it’s not removable?’ I didn’t know what grade it was. What if it’s spread somewhere else in my body? And I just had so many what-ifs in my mind that I just kept crying.”

Before being diagnosed with a suspected grade 2 glioma, Sarah-Jane had booked a £1,100 holiday to Ayia Napa with one of her friends through loveholidays, with flight bookings through British Airways.

Loveholidays booking dispute after Sarah-Jane’s cancer diagnosis

Sarah-Jane said: “I went to Ayia Napa last year and it was really good so we were set on [going] there. But it was last minute because it’s just finding time for us to be together and book holiday.

“I hadn’t been on holiday this year yet, we just wanted to get away so I’d not really had any annual leave or anything like that.

“Just wanted a break and plus because I would be starting a new training programme in September. I wanted to find a decompress before that.”

The day Sarah-Jane was diagnosed with cancer, she contacted loveholidays to make them aware and asked for a refund of her package. At the same time she realised her yearly travel insurance cover had not renewed as she thought it had.

She said: “The first time that we called they didn’t want to know at all. They didn’t even express empathy or anything like that. And then I got an email just saying I can get £62 back.”

Sarah-Jane then sent two letters from medical professionals, one from a consultant at the hospital, and a second from her GP, which were both rejected by loveholidays due to her first letter being a “statement for fitness for Work (SSP)” and the second being a letter that “outlined that it had been issued to support a travel insurance claim”.

Sarah-Jane’s TikTok video prompts action from loveholidays CEO office

After receiving pushback from loveholidays the 24-year-old made a video about her experience on TikTok, with a member of the CEO office at the company reaching out shortly after.

Sarah-Jane continued: “So it was just calls back and forth. They said you need to get in touch with British Airways. British Airways said it has to all be done through loveholidays.

“I asked them to speak to my mum, I just couldn’t deal with speaking to them. I couldn’t keep hearing no and saying, ‘there’s nothing we can do’.

“Then the person from the CEO office said ‘we wish Sarah the best and stuff’ which just shows that there’s no compassion.”

The company then offered Sarah-Jane a £300 refund, which her mum refused, before offering £600, which they also rejected. The following day, however, the loveholiday’s team confirmed they would offer Sarah-Jane a full refund.

She said: “She spent over eight hours on the phone, backwards and forwards, to loveholidays and British Airways because they just kept sending each other to each other. She started crying on the phone because the way people were speaking to her was just… It’s not what she needed to hear.

“She was unnecessarily sent between two different companies that both didn’t want to know. I think that just shows that more protection is needed in the event of major health diagnoses, because if it wasn’t for the TikTok then nothing would have been done.”

Loveholidays and British Airways issue official statements

A loveholidays spokesperson said: “We are deeply sorry to hear about Sarah’s diagnosis and the difficult circumstances she is facing. We wish her all the very best with her treatment and recovery.

“To support Sarah during this difficult time, we have refunded her in full for her holiday, and we have also explained how she can request a refund for the seat purchase she made directly with her airline.

“While we always do everything we can to support customers in difficult circumstances, as a travel agent we are bound by the cancellation policies of our airline and hotel partners, many of which do not provide refunds when customers are unable to travel due to illness.

“For this reason, we always strongly recommend that customers take out travel insurance to help protect them if unforeseen circumstances prevent them from travelling.”

A spokesperson from British Airways said: “We’re very sorry to hear of our customer’s experience and our teams have been in touch.”

The spokesperson also said that the airline had “resolved this matter”, however Sarah-Jane told us that she has yet to receive the refund or, indeed, any further communication from British Airways customer service.

July 2 (Asia Today) — South Korean researchers have developed an experimental prodrug that uses elevated hydrogen peroxide in brains affected by Alzheimer’s disease as a signal to activate treatment, KAIST said Thursday.

The compounds remained largely inactive under healthy brain conditions but became active therapeutic agents after encountering hydrogen peroxide associated with Alzheimer’s pathology. The researchers confirmed their effects in animal experiments.

The research was led by Mi Hee Lim, a professor in KAIST’s Department of Chemistry. The university worked with research teams led by Min Geun Kim of Chonnam National University, Chul Ho Lee and Kyung Sim Kim of the Korea Research Institute of Bioscience and Biotechnology and Young Ho Lee of the Korea Basic Science Institute.

A prodrug is an initially inactive compound that converts into an active treatment only under specific conditions in the body.

The research team designed its prodrugs to activate only when exposed to hydrogen peroxide, a reactive oxygen species found at elevated levels in brains affected by Alzheimer’s disease.

Hydrogen peroxide has generally been treated as a harmful substance that should be removed because it can damage cells. The researchers instead used it as a biological signal to switch on the treatment.

The two prodrugs, called BE-1 and BE-2, showed little reaction under healthy brain conditions. When exposed to hydrogen peroxide in an Alzheimer’s-like environment, they converted into active compounds known as AP-1 and AP-2.

The activation process reduced hydrogen peroxide and other reactive oxygen species. It also interfered with the aggregation of amyloid beta, a protein that can accumulate in the brain and form toxic clumps associated with Alzheimer’s disease.

Advanced analytical tests showed that the activated compounds altered the structure of amyloid beta and prevented it from developing into larger aggregates, the researchers said.

Tests using mice with Alzheimer’s-like conditions showed that the prodrugs crossed the blood-brain barrier, which regulates which substances in the bloodstream can enter the brain.

The compounds then converted into their active forms inside the animals’ brains. The findings demonstrated that the prodrugs could reach their intended target and respond to the disease-related environment.

The approach differs from treatments designed to act continuously against a single protein. Instead, the KAIST-led strategy uses conditions within diseased tissue to activate treatment only where it is needed.

Researchers said this targeted activation could provide a strategy for increasing therapeutic effects while limiting unnecessary activity in healthy tissue. KAIST said the technology could also have potential applications in treatments for Parkinson’s disease and other neurodegenerative disorders.

“This study is significant because it uses hydrogen peroxide, which had previously been regarded only as something that should be removed, as a signal that activates the drug,” Lim said.

“The technology, which activates drugs only in diseased tissue, could become a new platform for treating complex diseases such as Alzheimer’s more safely and effectively,” she said.

— Reported by Asia Today; translated by UPI

© Asia Today. Unauthorized reproduction or redistribution prohibited.

Original Korean report: https://www.asiatoday.co.kr/kn/view.php?key=20260702010001077

Samuel Monroe Jr., known for ‘90s cult classic films “Menace II Society” and “Tales from the Hood,” is fighting for his life after doctors misdiagnosed a meningitis infection.

Monroe’s wife, Shawna Stewart, confirmed the news with Complex, telling the outlet that the star contracted meningitis 18 months ago while filming in Las Vegas.

“He went to several different hospitals, where his condition was repeatedly misdiagnosed and because of this negligence, the meningitis went untreated for eight months,” Stewart told the outlet.

She said that by the time doctors properly diagnosed the actor, the infection had already spread “not only to his spine but also to his brain.”

According to the Mayo Clinic, meningitis is an infection and swelling of the fluid and membranes around the brain and spinal cord. The inflammation from meningitis typically triggers symptoms such as headache, fever and a stiff neck. While viral infections are the most common cause in the United States, bacteria, parasites and fungi can also cause the condition.

The family launched a GoFundMe on Monday, sharing that the financial strain has been “immense” and that over the last nine months, Monroe has been in multiple hospitals and two rehabilitation centers. According to the fundraiser, the actor will require around-the-clock care if he regains consciousness and is removed from life support.

“As the whole family and friends do not want to think negative in the event that Samuel is taken home by God,” Tayonna Stewart wrote on the GoFundMe. “Any funds raise would be put towards a proper and respectful celebration of life for his family, friends and fans to attend.”

The actor’s mom, Joyce Patton, also shared the news on Facebook and asked for prayers for her son.

“Please pray for Samuel Monroe Jr. my son who is now on life support,” she wrote on Saturday. “God don’t make no mistakes but he is gracious and I am humbly asking for his mercy and grace for Sam. I love you son … to the moon and back 100 times.”

At present, the GoFundMe has raised 7% of its $50,000 goal, with “Big Boy’s Neighborhood” radio host Kurt Alexander contributing $1,000.

Monroe, who has gone by the stage name “Caffeine” and “Caffamilliano,” landed his first acting gig in 1993, opposite Patti LaBelle on the hit TV series “Out All Night.” The same year, he splashed onto the big screen, portraying Ilena’s cousin in “Menace II Society.”

He’s also acted in films “Tales from the Hood,” “Don’t Be a Menace to South Central While Drinking Your Juice in the Hood,” “What Goes Around Comes Around,” “Set It Off” and “The Players Club.”

Most recently, he acted in 2023 films “Packz” and “Payment Received.”