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Bill Cassidy’s roles as a lawmaker, a doctor and a political candidate will collide on Wednesday as he questions Health Secretary Robert F. Kennedy Jr. in two high-stakes Senate hearings.

The Louisiana Republican chairs one of the Senate committees that oversees Kennedy’s department and sits on another, giving him two chances to interrogate the secretary about his plans for an agency responsible for public health programs and research. As a doctor, Cassidy has clashed with Kennedy’s anti-vaccine ideas even though he provided crucial support for the health secretary’s nomination last year.

At the same time, Cassidy is fighting for his political future in next month’s primary in Louisiana, where President Trump has endorsed one of his opponents in an unusual attempt to oust a sitting senator from his own party.

How Cassidy handles the hearings could affect his chances at a pivotal moment of his reelection campaign and set the tone for how Congress oversees the nation’s health agenda at a time of rampant distrust and misinformation.

Cassidy hasn’t faced Kennedy in public since September. In the subsequent months, Kennedy has attempted a dramatic rollback of vaccine recommendations that, if not blocked by an ongoing lawsuit, could undermine protections against diseases like flu, hepatitis B and RSV.

After a backlash, Kennedy has also pivoted to spending more time talking about less controversial topics like healthy eating — albeit with his own spin, including sharing exaggerated claims that various ailments can be cured by diet alone.

Cassidy will have to decide on Wednesday whether to grill Kennedy on vaccines, an issue deeply important to him, or put their differences aside and prioritize loyalty to the Trump administration.

“He’s taken a risk showing any sort of resistance to RFK,” said Claire Leavitt, an assistant professor at Smith College who studies congressional oversight. “He may pay an electoral price for that.”

Cassidy has long advocated for vaccines

Cassidy has spent years walking a political tightrope. He’s one of the few Republican senators who voted to convict Trump during an impeachment trial after the Jan. 6, 2021, attack on the U.S. Capitol.

As a liver doctor, he advocated for babies to receive hepatitis B vaccines shortly after birth, a step that could have prevented the disease in his patients. But when Trump nominated Kennedy, a longtime anti-vaccine activist, Cassidy supported him. He did so after securing various commitments, including that Kennedy would work within the current vaccine approval and safety monitoring system and support the childhood vaccine schedule.

The vote for Kennedy did not appear to mollify Trump. The president endorsed U.S. Rep. Julia Letlow, one of Cassidy’s two primary opponents.

Cassidy also faces opposition from Kennedy’s allies in the “Make America Healthy Again” movement, a group that includes both anti-vaccine activists and a wide variety of other crusaders for health and the environment. The MAHA PAC, aligned with Kennedy, has pledged $1 million to Letlow’s campaign. While the organization hasn’t publicly said so, some have questioned whether the support is partly in retaliation against Cassidy for criticizing Kennedy’s vaccine policy agenda.

“I’m not really sure what MAHA’s beef is,” Cassidy told reporters earlier this month. “Let me point out that I am the reason that Robert F. Kennedy is now the secretary of HHS. He would not have gotten there otherwise.”

Cassidy argues that he has “strongly supported” the MAHA agenda, especially when it comes to the fight against ultraprocessed foods. However, the physician-turned-senator acknowledged that he and MAHA have “disagreed on vaccines.”

“We’ve seen, frankly, that I am right,” Cassidy added, pointing to recent measles-related deaths of children who were not vaccinated.

At a hearing in September, he slammed Kennedy’s decision to slash funding for mRNA vaccine development. He interrogated Kennedy over his attempt to replace members of a vaccine committee, suggesting the new members could have conflicts of interest. He also raised concerns that Kennedy’s vaccine policy decisions could be making it harder for Americans to get COVID-19 shots.

Later that month, Cassidy convened a hearing featuring former U.S. Centers for Disease Control and Prevention Director Susan Monarez, who was ousted by Kennedy less than a month into her tenure after they clashed over vaccine policy, and former CDC Chief Medical Officer Debra Houry, who resigned in August citing an erosion of science at the agency.

“I want to work with the president to fulfill his campaign promise to reform the CDC and Make America Healthy Again. The president says radical transparency is the way to do that,” Cassidy said at the time.

Experts say Cassidy’s vaccine stance might not hurt him

Political consultants said they expect Cassidy’s primary opponents, Letlow and Louisiana Treasurer John Fleming, to seize on any sound bites from Wednesday’s hearings that can make Cassidy seem at odds with the Trump administration.

But Dorit Reiss, a vaccine law expert at UC Law San Francisco, said the political risk of advocating for vaccines may not be as strong among Republicans as some people assume.

“He’s probably not alienating voters by focusing on the issue and calling it out,” she said.

Louisiana political consultant Mary-Patricia Wray said she thinks most diehard MAHA voters already know who they are voting for, and it’s probably not Cassidy.

Instead, she said, he may still be able to appeal to Democrats who switch their party registration to vote in the primary, as well as a wide swath of still-undecided Republican voters who care about the same health care affordability issues he advocates for every day in Congress.

“If I was advising Bill Cassidy, I would tell him your goal here is not to get out unscathed,” Wray said. “Your goal is to prove that your consistency on issues regarding public health is an asset in your campaign, not a detriment.”

Election outcome will shape future oversight of HHS

Also at stake if Cassidy doesn’t make it to November’s general election is what will happen to his responsibility to oversee the massive U.S. Department of Health and Human Services as the chair of the Senate Health, Education, Labor and Pensions committee.

Leavitt, the Smith College professor, said seniority typically plays the most important role in who chairs Senate committees. She said another Republican in today’s increasingly hyperpartisan Congress may not be as willing as Cassidy to check Kennedy’s power.

Reiss, the vaccine law expert, said she wishes Cassidy had done more hearings or introduced legislation to rein in Kennedy. And she said the senator bears the blame for allowing Kennedy to bring unfounded vaccine fears into the government in the first place.

“His original sin, of course, was voting for Kennedy at all,” Reiss said.

Swenson writes for the Associated Press. AP writer Sara Cline contributed to this report.

April 16 (UPI) — Health and Human Services Secretary Robert F. Kennedy, Jr. on Thursday testified before seven congressional committees, often clashing with Democrats about decisions he has made about vaccines and department priorities.

The testimony is Kennedy’s first trip to the Capitol this year and the first time that he has appeared before Congress in more than seven months, The Washington Post reported.

In addition to unilaterally remaking the Center for Disease Control and Prevention’s vaccine advisory committee and the agency’s recommended childhood vaccine schedule — which were blocked by a federal judge in March — he has changed the Food and Drug Administration‘s recommendations on diet and shepherded medications through federal approval processes while allegedly ignoring data on them.

Kennedy also was asked by members of Congress about the Trump administration’s 12.5% budget request decrease, which amounts to about $16 billion that it sought for its fiscal year 2027 budget proposal, NPR reported.

“Our children are the sickest generation in modern history — decades of failed policy, captured agencies and profit-driven systems have caused it,” Kennedy said during a hearing before the House Ways and Means Committee.

“Parents across this country demanded change — and we are delivering it,” he said.

Kennedy said that the measles vaccine “certainly” could have saved the life of a child who died in Texas last year during an outbreak in the state.

More than 1,700 measles cases have been reported through the first 3 1/2 months of 2026, compared to more than 2,200 reported in all of 2025.

He also was asked by Rep. Linda Sanchez, D-Calif., about ending an influenza vaccine public awareness campaign while investing money in marketing efforts for his remade food pyramid.

“You suspended this pro-vaccine messaging campaign, but somehow you’re spending taxpayer dollars to drink milk, shirtless in a hot tub with Kid Rock?” Sanchez asked.

Kennedy also was accused of “diminishing science” by Rep. Bradley Scott, D-Ill., with his support for $5.7 billion in cuts to the National Institutes of Health meant for drug development.

“Nobody wants to make the cuts,” Kennedy said in response to several questions about reducing the HHS budget, but said the nation needs “to tighten our belt” because of the national debt, which he blamed on Congress.

Health Secretary Robert F. Kennedy Jr. on Thursday faced federal lawmakers for the first time since September as he sought to defend a more than 12% proposed cut to his department’s budget and dodge arrows from angry Democrats along the way.

In his testimony before the House Ways and Means Committee, kicking off an expected sprint of seven budget hearings he’ll attend across congressional committees and subcommittees over the next week, Kennedy emphasized the administration’s work to reform dietary guidelines and crack down on waste, fraud and abuse.

Republicans on the committee praised Kennedy as a “breath of fresh air” and asked him to promote his department’s recent actions. Democrats, who have been furious over Kennedy’s sweeping overhaul of the U.S. Department of Health and Human Services, largely had a different agenda.

They needled Kennedy on what they viewed as the Trump administration’s hypocrisy on fraud, demanded to know why he was cutting budgets for various programs and slammed his efforts to pull back vaccine recommendations and messaging, which they said have caused unnecessary deaths.

Kennedy fired back, often raising his voice as he accused the Democrats of misrepresenting his work and past statements.

Here are three standout moments from Thursday’s hearing:

A standoff over measles

One heated exchange early in the hearing came between Kennedy and Rep. Linda Sanchez. The California Democrat decried recent measles outbreaks across the U.S. and asked Kennedy to answer for the fact that under his leadership, the Centers for Disease Control and Prevention pulled back public health messaging supporting vaccination.

“As a mother, this horrifies me,” Sanchez said. “Did President Trump approve your decision to end CDC’s pro-vaccine public messaging campaign?”

Kennedy repeatedly refused to answer, saying first he wanted to respond to the “misstatements that you’ve made” and later praising the Trump administration’s record on preventing measles, although protections against the disease have eroded in some parts of the country as vaccination rates have dropped.

“That’s not answering my question,” Sanchez said as the two talked over each other.

But Sanchez also got Kennedy, a longtime anti-vaccine activist before he entered politics, to acknowledge that a 6-year-old who died of measles last year in West Texas could have potentially been saved with vaccination.

“Do you agree with the majority of doctors that the measles vaccine could have saved that child’s life in Texas?” she asked.

“It’s possible, certainly,” Kennedy said.

RFK Jr. denies talking about Black children being ‘re-parented’

A fight erupted between Kennedy and Rep. Terri Sewell, a Democrat from Alabama, when Kennedy vehemently denied making remarks he’d said in 2024.

The comments dated back to when Kennedy was a presidential candidate. On the “High Level Conversations” podcast last July, he said, “Psychiatric drugs — which every Black kid is now just standard put on Adderall, SSRIs, benzos, which are known to induce violence, and those kids are going to have a chance to go somewhere and get re-parented to live in a community where there’ll be no cellphones, no screens, you’ll actually have to talk to people.”

“Have you ever re-parented, or parented, I should say, a Black child?” Sewell asked, as her staff held up a poster featuring an abbreviated version of the quote.

“I don’t even know what that phrase means,” Kennedy said. “I’m not going to answer something I didn’t say.”

“You’re making stuff up,” he later claimed.

A recording of the podcast shows he made the comments during a conversation about free rehabilitation facilities he was proposing opening at the time in rural areas around the country.

Health and Human Services spokesperson Emily Hilliard said Kennedy before joining the administration was referring to spaces where young people facing alienation, mental health challenges and despair could get re-parented, which she said was a psychotherapy term for “developing the emotional regulation, discipline, boundaries, and self-worth that may not have been established in childhood.”

For Kennedy and his former party, civility is the exception

Kennedy spent most of his life as a Democrat, the scion of one of the nation’s most famous political families. Both Republicans and Democrats during the hearing began their remarks by expressing their admiration of Kennedy’s relatives, among them former President John F. Kennedy.

But again and again throughout Thursday’s hearing, the fraying of bonds between Kennedy and his former party was on full display as spiteful comments were passed back and forth.

The Health secretary grew defensive and visibly agitated. He repeatedly criticized Democratic lawmakers for not giving him a word in edgewise.

“They’ve all shut me up,” Kennedy said at one point. “They give a little speech that they can go and market, you know, for fundraising, and they don’t allow me to answer the question.”

On a few rare occasions, the exchanges were civil. One representative, Gwen Moore of Wisconsin, used humor to make that happen.

“I promise to give you easy, comfortable questions if you don’t yell at me and hurt my feelings,” she told Kennedy. He promised he wouldn’t.

Swenson writes for the Associated Press.

WASHINGTON — The Food and Drug Administration will hold a meeting in the summer to consider easing restrictions on more than a half-dozen peptide injections, a group of unapproved therapies that have become popular among wellness influencers, fitness gurus and celebrities.

The meeting announcement Wednesday follows repeated pledges by Health Secretary Robert F. Kennedy Jr. to loosen regulations on peptides, which are often pitched as a quick way to build muscle, heal injuries or appear younger. There’s little research behind those claims and most peptides have not been reviewed for safety by the FDA.

Kennedy has discussed using peptides for his own injuries. And some major supporters of his Make America Healthy Again movement are big proponents of them, including Gary Brecka, a self-described “longevity expert” who sells various peptide formulas through his website.

The FDA said in a federal notice Wednesday that it will ask a panel of outside advisors to review seven peptides at a meeting in July, specifically whether they should be added to a list of substances that can be safely produced by pharmacies. In the meantime, the agency said it would soon remove the chemicals from a restrictive list reserved for unapproved, high-risk drugs. The peptides under discussion include some of the most popular among influencers, such as BPC-157, which is marketed to heal injuries and reduce inflammation.

“The Wild West is about to become wilder,” said Dr. Peter Lurie, a former FDA official who now leads the Center for Science in the Public Interest. In an interview, Lurie said allowing peptides on the market without clinical testing poses a “profound threat” to FDA’s decades-old system for vetting drugs.

“I don’t see why one would take the path of a proper drug approval if there is now this less rigorous, alternative path to market,” he said.

Under President Biden, the FDA added nearly 20 peptides to the federal list of substances that should not be produced by compounding pharmacies — businesses that mix medications that aren’t available from drugmakers.

At the time, the FDA’s panel of pharmacy advisors voted overwhelmingly that the peptides did not meet the criteria for substances that can be safely compounded. And FDA regulators agreed, saying later that the substances “present significant safety risks,” because most have not been extensively tested in humans.

Many of the FDA advisors and internal staff who oversaw those decisions no longer work for the agency. The FDA’s pharmacy panel currently has a number of vacancies, which Kennedy could fill before the July meeting.

Kennedy previewed Wednesday’s move in an interview with podcast host Joe Rogan. Both men have repeatedly spoken about peptides and claimed to have benefited from their use.

RFK Jr. claims personal benefit from peptides

“I’m a big fan of peptides,” Kennedy told Rogan. “I’ve used them myself and with really good effect on a couple of injuries.”

Given Kennedy’s statements, Lurie said it was doubtful the drugs would receive real scrutiny from FDA.

“Everybody knows the outcome that the secretary wants,” Lurie said. “I don’t believe for one moment that what’s going on here is an honest investigation of whether these products should be compounded.”

Scott Brunner of the Alliance for Pharmacy Compounding said the coming meeting will be the start of a “protracted process.” Even if the panel votes to make the peptides available, and the FDA agrees, the agency will still have to draft and publish rules on the change, he noted.

Peptides are essentially the building blocks of more complex proteins. Inside the human body, peptides trigger hormones needed for growth, metabolism and healing.

In recent years peptides have become widely known through the blockbuster success of GLP-1 medications, which the FDA has approved for treating obesity and diabetes. Other FDA-approved peptides include insulin for diabetics and hormone-based drugs for several medical conditions.

But many of the peptides promoted online have never been approved, making them technically illegal to market as drugs. Several peptides, such as BPC-157 and TB-500, are banned by international sports authorities as doping substances.

But that has not stopped them from gaining a foothold in the burgeoning marketplace for wellness hacks and alternative remedies.

“I think this is a disaster in the works,” said Dr. Eric Topol of Scripps Research Translational Institute, who has studied the issue. “These peptides have no data to support their safety and efficacy.”

Meanwhile, some dietary supplement makers have begun mixing peptides into capsules, protein powders and gummies. At a recent FDA meeting, the industry argued for expanding the federal definition of supplements to permit the use of newer ingredients such as peptides in their products.

Safety risks were cited previously

When the FDA added a number of injectable peptides to its list of restricted substances in 2023, it cited safety risks including cancer and liver, kidney and heart problems.

That triggered pushback from wellness entrepreneurs, compounding pharmacies and their allies in Washington.

Last year several members of Congress, including Republican Sen. Tommy Tuberville of Alabama, sent letters to Kennedy asking him to lift limits on peptide production.

Some in the compounding industry argue that FDA restrictions have given rise to an illicit market of imported chemicals from China and other countries, which are not subject to U.S. drug standards.

Kennedy has echoed those concerns.

“With the gray market you have no idea if you’re getting a good product,” Kennedy told Rogan. “And a lot of this stuff that we’ve looked at is just very, very substandard.”

Perrone writes for the Associated Press.

NEW YORK — Health Secretary Robert F. Kennedy Jr. is launching a new podcast that he says will begin “a new era of radical transparency in government,” according to a teaser video first obtained by the Associated Press.

The show, titled “The Secretary Kennedy Podcast,” will launch next week and feature Kennedy in conversation with doctors, scientists and agency staff, U.S. Department of Health and Human Services officials told the AP ahead of the launch. In the teaser video, in a slick Health and Human Services-branded studio with ominous music playing in the background, Kennedy bills it as a new way to expose corruption and lies that have made Americans sick.

“We’re going to name the names of the forces that obstruct the paths to public health,” Kennedy says in the 90-second clip.

The new communication effort from the Department of Health comes as the department has faced a bevy of recent setbacks, including widespread criticism of its vaccine policy changes, a federal ruling last month blocking several of those moves, and resistance from key Republican senators that has kept President Trump’s surgeon general pick from taking office. In that way, it could be seen as part of a broader rebranding strategy as the agency redirects away from vaccine efforts and toward a less contentious agenda on healthy food ahead of November’s midterm elections.

But the show, which has been in the works since early in the second Trump administration, also reflects Kennedy returning to a format where he has long felt at ease. An antivaccine crusader and attorney before he entered office, he previously hosted his own podcast and has appeared on dozens to share his perspectives in longform interviews, as recently as this week.

Tyler Burger, Health and Human Services digital communications manager and the producer of the new podcast, said while Food and Drug Administration Commissioner Marty Makary has a podcast, officials believe Kennedy’s will be the first to be hosted by a sitting Cabinet secretary.

“We’re kind of bringing podcasting into the government as an official form and arm of our messaging,” Burger said. He said the set for the show was pieced together largely with items the agency already had, and has the capacity for a total of four people to sit in conversation together.

“This is part of our larger strategy to bring the Make America Healthy Again message to as wide an audience as we can,” said Liam Nahill, Health and Human Services digital director.

Because podcasts are now commonly made not only on audio but video, they are regularly clipped and shared across social media platforms, giving them “massive” reach, according to Melina Much, a postdoctoral fellow for NYU’s Center for Social Media and Politics.

Much said podcasts also tend to be more intimate, conversational and friendly than a traditional interview, allowing administration officials to promote themselves without facing as much pushback.

While Kennedy’s teaser focuses on uncovering lies, Health and Human Services spokesman Andrew Nixon said it will aim to cover affordability and other topics that polls show are salient for American voters ahead of the midterms.

“Americans are united on the need to urgently address chronic disease, improve nutrition, strengthen food quality, and lower health costs,” he said. “The Secretary Kennedy Podcast will cover all those issues.”

Swenson writes for the Associated Press.