pause

May 2 (UPI) — A company that makes the abortion drug mifepristone on Saturday asked the U.S. Supreme Court to immediately pause a ruling that prevents doctors from prescribing it during telehealth visits.

Late Friday, a three judge panel on the 5th Circuit Court of Appeals unanimously ruled in favor of the state of Louisiana in a case asking the court to block doctors from prescribing the drug in telehealth visits.

Louisiana in the last four years has moved to prevent women in the state from obtaining abortion care legislators there were among the first to ban abortion after the repeal of Roe v. Wade, and later blocked doctors from prescribing the medical abortion pill in virtual telehealth visits.

The company, which is not the only drugmaker planning to file an appeal, said that patients will be stuck in limbo because of the lack of clarity it leaves for legal use of the drug, NBC News and Politico reported.

Roughly half of all abortions in the United States are performed using medications.

“Danco has been free to rely on procedures set by the FDA to distribute its product,” lawyers for the company said in a filing with the court.

“The Fifth Circuit’s decision immediately ends that,” the lawyers said. “A stay should issue to prevent the disruption and confusion that will result if the decision below were to remain operative.”

In addition to Danco, Politico reported that GenBioPro, which also manufactures the drug, has indicated that it will also file an appeal with the court.

Mifepristone was approved by the U.S. Food and Drug Administration in 2000 for medical termination of pregnancy and, until the COVID-19 pandemic, could only be prescribed during in-person appointments.

Early in the pandemic and the country locked down in an effort to stem the spread of the virus, doctors sued the FDA to allow them to prescribe mifepristone during telehealth visits.

The FDA temporarily changed the rule, but in 2023 adopted it permanently as some states started to restrict access to abortion and abortion services after the Supreme Court struck down Roe v. Wade.

Pharmaceutical companies and patient advocates warned that the restriction circumvents the FDA’s regulatory authority, which is based on evidence and data, and that it may offer a path for people to challenge other medications based on personal interest or opinion.

In the case of Danco, it also immediately filed the appeal because it is the only product it makes and “without a valid legal framework for distributing that product, Danco will lose its only source of revenue and may be unable to continue operating.”

The U.S. Navy says it is still aiming to see the AGM-88G Advanced Anti-Radiation Guided Missile-Extended Range (AARGM-ER) enter operational service this year. This is despite the announcement of a planned “strategic pause” in purchases of the missiles in the 2027 Fiscal Year. AARGM-ER is set to give Navy carrier air wings a critical boost in their ability to neutralize ever-more capable hostile integrated defense networks.

AARGM-ER has been in the works since the late 2010s. Northrop Grumman is the current prime contractor, through its previous acquisition of Orbital ATK. The Navy has ordered dozens of the missiles already. Hence, it was very surprising when the service’s latest proposed budget for the 2027 Fiscal Year, rolled out in full last week, included no request for funding to buy more AGM-88Gs due to the aforementioned pause. All of this, coupled with previous delays and technical issues encountered in testing, had prompted new questions about the future of the program.

“U.S. procurements for the AARGM-ER program are planned to resume once the system has successfully completed all necessary testing and software updates. Our immediate priority is ensuring the weapon passes these rigorous testing milestones to achieve Initial Operational Capability (IOC) in September 2026,” a Navy spokesperson told TWZ. “After validating the software and testing, the plan would be to ramp up production to clear a backlog of over 150 missiles, with U.S. procurements officially restarting in FY28 [Fiscal year 2028]. In the interim, FY27 production will be allocated to Foreign Military Sales to fulfill our commitments to five signed international cases.”

The spokesperson did not name the foreign customers in question. However, Italy is a full partner in the development of the AGM-88G. The U.S. government has also previously approved sales of the missiles to Australia, Finland, and the Netherlands. Norway has publicly announced its intention to purchase AARGM-ERs, as well. The U.S. Air Force is also set to acquire these missiles. We will come back to this later on.

The AGM-88 family, also known as the High-speed Anti-Radiation Missile (HARM), traces its roots back to the 1970s. The AARGM-ER is a major redesign of the preceding AARGM variant, also designated the AGM-88E. The AGM-88G features a completely redesigned body optimized for high speed and range, as well as a new, more powerful rocket motor and control actuation system.

Inside, the AGM-88G reuses the guidance and control systems from the AGM-88E. By extension, this means the AGM-88G retains the same multi-mode guidance capability of its predecessor, which includes a GPS-assisted inertial navigation system and a millimeter-wave radar seeker. The AARGM-ER’s primary target set is hostile emitters, especially air defense radars, but the guidance package is designed to allow it to find its mark even if they shut down and stop sending out signals to home in on. The AGM-88E also has a more general, secondary ability to strike targets on land or at sea, including by just being directed to hit a specified set of coordinates.

AARGM F-18

The Navy sees the AGM-88G entering service first integrated with its F/A-18E/F Super Hornet fighters and EA-18G Growler electronic warfare jets, both of which can already employ the AGM-88E. AARGM-ER’s boosts in speed and range are seen as critical to ensuring the survivability and effectiveness of those non-stealthy aircraft in the face of an ever more capable air defense threat ecosystem.

AARGM-ER is also sized to allow for internal carriage on F-35A and C variants. There are plans to eventually integrate it for external carriage on all three F-35 variants, as well as legacy F/A-18C/D Hornets, as well.

As noted, the development of the AARGM-ER has had to contend with technical issues and delays over the years. Originally, the goal was to reach IOC on F/A-18E/F and EA-18G in Fiscal Year 2023.

“The AARGM-ER experienced significant delays as a result of rocket motor, structural, and software problems discovered during testing,” the Government Accountability Office (GAO) said in a report published in June 2025. “Contracting officials noted that the program worked with the prime contractor to investigate the root causes of the identified deficiencies and implement corrective actions, including changes in the production process.”

“The program is still experiencing production delays as well. Since our last assessment, program officials stated that testing issues, supply chain challenges, and construction delays for a new production facility slowed completion of the first two production contracts by 1 year,” GAO’s report added. “We have found that starting production before demonstrating a system will work as intended – which the Navy did – increases the risk of discovering deficiencies that require costly, time-intensive rework.”

“In FY25 [Fiscal Year 2025], the [AARGM-ER] program attempted three IT [integrated test] weapon employment tests using F/A-18F aircraft against a threat-representative integrated air defense land target at the China Lake Range in California,” according to a separate report from the Pentagon’s Office of the Director of Test and Evaluation (DOT&E), released in March of this year. “AARGM-ER successfully completed one of the three weapon events but exhibited performance discrepancies during the other two, to include one event during which range safety terminated the weapon after release. No further weapons employment testing was accomplished in FY25 pending implementation of updates required to address the problems that were identified.”

DOT&E warned in that report that the IOC schedule for AGM-88G could slip further to the first quarter of Fiscal Year 2027, which starts on October 1 of this year.

Earlier this year, the Navy somewhat urgently put out a contracting notice saying it was exploring options for a new long-range anti-radiation missile. The stated requirements for this Advanced Emission Suppression Missile (AESM) were very much in line with how the AARGM-ER has been discussed in the past, with one notable exception: a new demand for the ability to engage targets in the air, as well as on the surface. You can read more about why that is significant here. With the Navy confirming that it is still pushing ahead on AARGM-ER, it remains unclear how exactly the service sees ASEM fitting into its broader plans. There does not appear to be any explicit mention of ASEM in the Navy’s latest budget request.

As noted, the U.S. Air Force is also in line to acquire AGM-88Gs. An AARGM-ER subvariant with “improved warhead/fuze” is set to serve as a bridge to the Stand-in Attack Weapon (SiAW), as well. Reportedly now designated the AGM-88J, SiAW is a derivative of the AARGM-ER being developed to provide a broader high-speed strike capability. The Air Force expects to primarily employ SiAW against time-sensitive and/or high-value assets on the ground, especially ballistic and cruise missile launchers, air and missile defense nodes, electronic warfare systems, and even anti-satellite weapons.

Despite the Navy’s “strategic pause” with AARGM-ER, the Air Force is asking for more funds to purchase additional SiAWs in Fiscal Year 2027. The Air Force has said in the past that it has been targeting 2026 for reaching IOC with SiAW on the F-35A. SiAW flight testing to date, at least that has been disclosed, has involved carriage by F-16 fighters, and it is possible the missile could be integrated operationally onto that aircraft and others, as well. As an aside, Northrop Grumman has also been pitching a ground-launched member of the AARGM-ER/SiAW family, called the Advanced Reactive Strike Missile (AReS).

As mentioned, the Navy has made clear that procurement of AARGM-ERs for foreign customers through the FMS program is also continuing.

Time will tell whether or not the Navy can meet its IOC target for AARGM-ER by September, or the timeline slips into the next fiscal year. Still, the service looks to remain committed to the program, at least for the time being, regardless of its intent to put a year-long pause on buying more AGM-88G.

Contact the author: joe@twz.com

US President Donald Trump says he has agreed to extend his threatened deadline to attack Iran by two weeks, if Iran immediately re-opens the Strait of Hormuz. His Truth Social post came less than two hours before he had said Iran would face widespread attacks on civilian infrastructure.

Pakistan’s Prime Minister Shehbaz Sharif says diplomatic efforts to resolve the US-Israeli war on Iran are ‘progressing steadily’ as he urged US President Donald Trump to postpone his threatened deadline for two weeks. Al Jazeera’s Osama Bin Javaid explains Islamabad’s ‘last-ditch effort’.

Call The Midwife bosses will replace the much loved festive episode with a prequel show of the historical BBC drama series as it attempts a ‘temporary pause’

Call The Midwife bosses have decided to shake up the Christmas schedule by removing the much loved historical drama from the winter TV schedule. Now, viewers will be treated to a prequel episode titled Sisters In Arms which is said to be replacing the coveted prime time slot.

The prequel is set in the period of World War II and it seems it will feature the younger versions of the older characters, who have become fan favourites. The characters may include Fred Buckle, Dr Turner, Sister Julienne, Sister Evangelina and Sister Monica Joan.

It has been speculated that the prequel could also focus on Nurse Trixie Franklin’s story, who is played by the highly acclaimed actress Helen George. In the upcoming show, Helen George’s character will be played another actress reportedly in her teens or early twenties.

READ MORE: Miranda Hart’s ‘secret talks for Strictly Come Dancing job’ after huge reshuffleREAD MORE: Inside Call the Midwife prequel from release window to plot as three nuns return

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The show creator and writer Heidi Thomas confirmed plans of the shake-up, according to The Sun. She previously said: “No, there won’t be a Christmas special this Christmas, not in the traditional mould.” She added: “This is really just a very temporary pause in the usual pattern.”

Showrunner Heidi previously explained: “The opening of new doors at Nonnatus House feels profoundly emotional, and yet just right. I have never run out of stories for our midwives, and I never will.”

She added: “But having wept, laughed, and raged my way from 1957 to 1971, I found myself yearning to delve into the deeper past. The Blitz years in the East End were extraordinary – filled with loss, togetherness, courage and joy.”

Heidi continued: “The bombs fell, the babies kept on coming, and the Sisters kept on going. There will be so much in the prequel for our wonderful, loyal fans, including the appearance of some familiar (if much younger!) faces.

Series 15 of the show took viewers on an emotional journey as Sister Monica Joan died. The character was played by Judy Parfitt since the show first aired in 2012. The plot follows the lives of a group of nurses and midwives in East London, who made it their mission to care for the people of the East End.

Not only is there a prequel to be aired later this year but the hit show will also become a film, set overseas in 1972. However, a release date for the movie has not yet been confirmed.

Speaking to the Radio Times, Heidi said the film is about “strong women above all else.” She then admitted: “Everything changes and nothing changes,” she observed, recognising its connections to the most recent series.”

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March 27 (UPI) — Iranian Foreign Minister Abbas Araghchi said Friday that his country “will exact [a] heavy price” for Israeli strikes on infrastructure Friday.

In a post on X, he said the strikes hit two of Iran’s largest steel factories, a power plant, civilian nuclear sites and other infrastructure.

“Israel claims it acted in coordination with the U.S.,” Araghchi wrote.

The airstrikes came less than a day after U.S. President Donald Trump extended a pause on U.S. attacks on Iran’s energy sites for 10 days. Trump said he extended the deadline because negotiations between the United States and Iran had been going “well,” and Iran had permitted several oil tankers to transit the Strait of Hormuz.

The “attack contradicts POTUS extended deadline for diplomacy,” Araghchi wrote.

“Iran will exact HEAVY price for Israeli crimes.”

The Guardian reported that the airstrikes hit the Khondab heavy-water plant near Arak and a uranium production facility in Ardakan. They also hit steel plants in Khuzestan and Mobarakeh.

Iran’s state-run Tasnim news agency said Tehran was considering launching attacks on six steel factories in Israel in retaliation for Friday’s attack.

The Israeli military said Friday it had intercepted missiles launched by Iran, NBC News reported.

“A short while ago, the [Israel Defense Forces] identified missiles launched from Iran toward the territory of the State of Israel,” the military said in a statement. “Defensive systems are operating to intercept the treat.”

Speaking Friday evening at the Future Investment Initiative in Miami, Trump said Iran is “on the run,” one month after the United States and Israel jointly began attacking the country. The violence came amid negotiations in which the United States sought to limit Iran’s nuclear program.

“Tonight, we’re closer than ever to the rise of the Middle East that is finally free at least from Iranian terror, aggression and nuclear blackmail,” Trump said.

Iran is “being decimated,” he added.

“We are talking now, they want to make a deal.”

The United States offered a proposed 15-point peace plan to Iran this week, but Araghchi said Iranian officials had no plans to negotiate it “for now.”

“This is Israel’s war, and people of the region and people of the U.S. are paying the price for it,” he said.

Iran’s Red Crescent Society reported Friday that more than 70,000 residential units, 600 schools and 300 health facilities had been damaged since the start of the war.