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Wade Meckler and Jo Adell keyed a five-run second inning with two-run doubles, and Walbert Ureña navigated heavy traffic through five shutout innings to lead the Angels to a 10-1 victory over the Houston Astros on Tuesday night.

Houston put two runners on in the first, second and fifth and loaded the bases in the third, but Ureña (4-4) pitched out of each jam to lower his ERA to 2.44 on the season and 1.84 in eight starts since early May.

The 22-year-old right-hander gave up three hits, struck out seven and walked five in his 107-pitch effort, which included a 97-mph fastball to whiff Joey Loperfido with the bases loaded to end the third.

The Angels scored two unearned runs off starter Kai-Wei Teng (3-5) in the first, one when Nolan Schanuel was hit by a pitch with the bases loaded and the other on Oswald Peraza’s RBI grounder.

Backup catcher Sebastián Rivero sparked the Angels’ second-inning rally with a one-out single. Zach Neto was hit by a pitch and Mike Trout ended an 0-for-22 slump with a single to load the bases.

Meckler doubled to left-center for two runs and a 4-0 lead. Adell doubled to left to make it 6-0, and Peraza’s RBI groundout extended it to 7-0.

The Angels added three insurance runs in the eighth on Trey Mancini’s sacrifice fly and RBI groundouts by Peraza and Denzer Guzman. Relievers Brent Suter, Drew Pomeranz and Kirby Yates covered the final four innings.

Schanuel, who has been slowed by a left ankle injury, exited after three innings because of left calf tightness.

Rivero, who also singled in the third and has seven hits in his last seven at-bats, was removed in the fifth because of a left wrist injury.

Jack Kochanowicz to have Tommy John surgery

Angels pitcher Jack Kochanowicz needs Tommy John surgery, the team said Tuesday, and the 25-year-old right-hander is expected to be sidelined through the 2027 season.

The Angels also said that third baseman Yoán Moncada will have surgery on his balky right-knee. But, the specifics of the procedure and a timetable for the switch-hitter’s return were not known.

Kochanowicz went 2-5 with a 6.19 ERA in 13 starts this season, striking out 47 and walking 36 in 64 innings.

The hard-throwing sinker-ball specialist went 2-1 with a 3.05 ERA in his first seven starts, but was ineffective during his next six starts, going 0-4 with an 11.91 ERA, striking out 17 and walking 15 in 22 2/3 innings.

Kochanowicz’s fastball averaged 97 mph and touched 99 mph against the Dodgers, but he said after the game that his arm bothered him when he threw his changeup.

“Honestly, I didn’t think this was in the cards,” Kochanowicz said before Tuesday’s game against Houston. “I really thought it was just a little angry.

“I mean, my velo was fine, the fastballs, everything was fine. It really was just the changeup.

“I thought it was just kind of general soreness. … I thought I was going to hear back today that it was all right, but man, it is what it is.”

Manager Kurt Suzuki said the Angels are “still evaluating” their options for Kochanowicz’s replacement in the rotation. Among the candidates are left-hander Sam Aldegheri and triple-A right-handers Caden Dana and George Klassen.

Moncada, 31, who signed a one-year, $4-million deal with the Angels in February, was placed on the injured list because of right-knee inflammation on May 22 and transferred to the 60-day injured list on Monday.

He hit .189 with a .605 OPS, three homers and 10 RBIs in 41 games.

Wade Meckler and Nick Madrigal each had four of the Angels’ 16 hits, Walbert Ureña pitched six solid innings and the Angels beat the Colorado Rockies 11-4 on Wednesday night.

Meckler is batting .389 (14 for 36) with two homers and 10 RBIs since he was recalled from double-A on May 22.

Vaughn Grissom added a homer and three RBIs, and Oswald Peraza had two hits and two RBIs to help the Angels — who tied their season high with the 16 hits — avoid a three-game sweep.

Ureña (3-4) gave up three hits and three runs. He struck out seven and walked three, cooling a Colorado lineup that scored 39 runs in its previous five games. The 22-year-old right-hander, who moved from the bullpen to the rotation in mid-April, has a 2.08 ERA in his last seven starts.

The Angels bunched six hits in a six-run second, the rally featuring Jose Siri’s RBI double and RBI singles by Logan O’Hoppe, Grissom and Peraza. Two runs scored on wild pitches by Michael Lorenzen (2-8), who gave up eight runs and 10 hits in 3 1/3 innings.

The Rockies cut it to 6-1 on back-to-back doubles by Hunter Goodman and Troy Johnston in the fourth, but the Angels countered with Grissom’s two-run homer in the bottom of the inning for an 8-1 lead.

Colorado pulled to 8-3 in the fifth on Tyler Freeman’s two-run homer, but the Angels answered again in the bottom half on Jo Adell’s RBI single for a 9-3 lead. Doubles by Meckler and Peraza and Madrigal’s RBI single pushed the lead to 11-3 in the sixth.

Relievers Drew Pomeranz, Ryan Zeferjahn and Kirby Yates covered the final three innings for the Angels.

Mike Trout hit a two-run homer, Nolan Schanuel added an RBI double and the Angels clinched a series win with a 5-2 victory over the Texas Rangers on Saturday night.

Zach Neto walked to open the bottom of the first inning before Trout launched his 13th home run over the center-field wall for a 2-0 lead. Neto scored again in the fifth on Schanuel’s double to make it 3-1.

Schanuel exited after his hit with left calf tightness. Vaughn Grissom took over at first base.

Oswald Peraza added insurance in the eighth with a two-run single.

Walbert Ureña (2-4) threw five innings, yielding one run and five hits while striking out six. Kirby Yates earned his first save of the season by pitching a hitless ninth.

Nathan Eovaldi (5-5) gave up three runs and five hits in seven innings while striking out six for the Rangers.

Ezequiel Duran hit a sacrifice fly in the second for Texas’ first run, and Kyle Higashioka added his third homer in the seventh on a 395-foot shot to center.

The Angels had more hits (eight) than strikeouts (six) for the second consecutive game and have won two in a row for the first time since May 5-6.