The Old Trafford legend saw Erik ten Hag‘s wasteful side made hard work of Monday’s 2-0 FA Cup win at Wigan.
And the former midfield hardman tackled major areas of concern for manager Ten Hag as well as Ratcliffe.
INEOS owner Ratcliffe’s 25% United takeover has been confirmed, subject to approval by football chiefs, but any major squad shake-up won’t come until next summer.
And with United only eighth in the Premier League, as well as out of the Champions League, Keane delivered a withering assessment.
The pundit told ITV: “It can’t be any worse than it has been over the last few years in terms of decision making, people making decisions upstairs in regard of recruitment, the fees they’ve been paying out, the wages they’ve been handing out.
“You hope there’s a change of dynamics at the club, new opinions. But only time will tell.”
And just ahead of a third-round victory at the League One Latics, Keane derided the Red Devils for lacking unity on the pitch.
He said: “I don’t think they play like a team.
“They have got a lot of very good players, but we have seen how inconsistent they are.
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“They have lost a lot of games this year. Every time they get into an arm wrestle in any game they always seem to go under.
“They are talented players, no doubt, but they are not a team.”
But the ex-Ipswich and Sunderland manager claimed the Red Devils have also been unlucky, albeit making big mistakes on the transfer front.
Keane, 52, said: “They have had plenty of excuses over the past year with recruitment, ownership of the club and injuries.”