PITTSBURGH —  Patrick Mahomes passed for 320 yards and three touchdowns and the Kansas City Chiefs locked up the top playoff seed in the AFC for the fourth time in seven seasons with a 29-10 win over the Pittsburgh Steelers on Wednesday.

The two-time defending Super Bowl champions raced to an early 13-point lead and were never really threatened by the Steelers (10-6), who have dropped three straight as their chances of capturing the AFC North took another hit.

Mahomes connected on first-half scoring tosses to Xavier Worthy and Justin Watson and Kansas City’s defense did most of the rest even with perennial All-Pro defensive end Chris Jones sitting out while nursing a calf injury. The Chiefs sacked Russell Wilson five times, forced two turnovers and hardly looked gassed while playing for the third time in 11 days.

Travis Kelce caught eight passes for 84 yards while becoming the third tight end in NFL history to reach 1,000 receptions, joining Hall of Famer Tony Gonzalez and Jason Witten. Kelce sealed Kansas City’s fifth straight victory with a 12-yard touchdown grab early in the fourth quarter.

The 35-year-old celebrated by dunking the ball over the goal post, which drew an unsportsmanlike conduct penalty and groans from a capacity crowd at Acrisure Stadium that has grown used to seeing Mahomes toy with the hometown team. Mahomes is now 4-0 against the Steelers in his career, with 17 touchdowns against one interception.

Russell Wilson threw for 205 yards for Pittsburgh. George Pickens finished with three receptions for 50 yards after missing three games with a hamstring injury. It wasn’t nearly enough for the Steelers, who went 0-3 during a brutal three-game stretch against Super Bowl contenders Philadelphia, Baltimore and Kansas City.

Perhaps more troubling than the losses is the way they played out. The Steelers lost each game at least 14 points and could start the playoffs on the road after playing fast-and-loose with the two-game division lead they had just three weeks ago.