Wolves’ squad has been hit by a virus before Liverpool’s Premier League visit on Saturday.
Goalkeeper Dan Bentley was ill last week and several of his team-mates are now major doubts for the Molineux clash.
Boss Gary O’Neil, whose side are winless and bottom of the table, did not reveal who could miss the game, but said some players will need to be assessed on Saturday morning.
“There is quite a bit of illness at the moment, there are a few who will need a check on how they are feeling,” he added. “Quite a few missed training today [Friday].
“Some of the lads will struggle for tomorrow, whether they don’t quite make it or are not fit enough to start. Sometimes it can clear up in 24 hours.
“We are hopeful that all of the guys who have had something over the last couple of days will be fine. But, as the doctors told me, at this stage it’s difficult to give a definitive answer.”
Defender Yerson Mosquera is expected to be out for the season with a serious knee injury so 20-year-old Alfie Pond, who made his full debut in the Carabao Cup defeat at Brighton last week, could start against the second-placed Reds.
Struggling Wolves are one of six teams looking for their first win of the season, but O’Neil added: “I’m not fazed at all. I’m looking forward to the next part of it.
“First thing is you have to accept where you are. So we accept where we are at this moment and then we fight with everything we have to improve it.
“We have to get the group in the best spot possible for Liverpool and then give absolutely everything to try and improve our points tally.”