A woman has been found dead in a hotel room at Perth’s Crown Casino complex, prompting a homicide investigation.

Police say they were called to the Crown Towers hotel in Burswood about 11:10am on Monday, where a woman in her 30s was found dead inside a room.

St John Ambulance said they also took a man in his 40s to Royal Perth Hospital as a priority one urgent case.

Police said that man was found inside the same room with self-inflicted injuries.

He is in police custody in hospital.

It is believed both people are known to each other.

The Homicide Squad is investigating the incident.