The pound-for-pound great has never competed outside of Mexico or America during his legendary career.
He has beaten all eight of his English opponents that have travelled across the pond to challenge him.
Now, Canelo is looking to add further damage by crossing into enemy territory for a massive fight in the capital.
In an exclusive interview with SunSport, he said: “I am thinking about one day fighting in London, yes. I’d love to go to London.
“But the opponent? I don’t even think about it yet.”
Father-of-four Canelo – an avid golfer in his spare time – has been bullish about retiring before his 40th birthday.
But even as a four-division champion and the world’s highest-paid fighter, still the modern day icon finds more to strive for 63 bouts later.
He said: “I always say 37 or 38 is a good number (to retire on).
“Just still win fights, still be in these kind of big fights that motivates me. There’s always something there to achieve, keep winning and that’s it.”
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Canelo has jumped through the weights during his career, winning his first piece of gold in the 154lb light-middleweight division.
He even went as high as 175lb to claim the WBO light-heavyweight title in 2019.
But it was there he later lost to Dmitry Bivol, 32, two years later which caused him to turn his attention back to super-middleweight.
Canelo, 33, reigns at 168lb with all four titles having last beaten Britain’s John Ryder, 35, at his Mexican homecoming in May.
Now, he is set for a historic battle of the undisputed against Jermell Charlo, 33, who will jump TWO weights for the fight.
American Charlo also has all four belts at 154lb, marking the first time two fully unified champions have shared the ring.
Ahead of the Showtime PPV, Canelo said: “I expect the best from him.
“He has everything; he knows how to move in the ring, he knows how to box, he knows how to throw the punches, he knows how to counter punch, he knows how to go forward.
“He has everything but I’ve fought with everybody out there and I have the experience to adapt myself to every style. I think it’s going to be a good fight.”