Ramos, 21, has been heavily linked with a move to Old Trafford after bursting onto the International stage at the Qatar World Cup following a hat-trick in the Round of 16.
The Benfica ace has enjoyed a stellar year at club level too.
However, Portugal team-mate Fernandes has backed Ramos to thrive in the Premier League, declaring “he has all the qualities” needed to play in England‘s top flight.
Speaking to A Bola, the Red Devils vice-captain said: “The best always come in handy, be it Gonçalo or another player.
“He has all the qualities to play in the Premier League, and when I say Premier League I also mean Manchester United.
“I think he could become a great reference in the coming years, but it’s still not in my hands to be sports director…
“Gonçalo has all the conditions to play in the Premier League, he is very intense, presses very well and is very good inside the area.”
Ramos has bagged 27 goals and 12 assists across 47 games for the Eagles this season.
And a reported move for the striker could see United splash as much as £103million on him (€120m).
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The Red Devils are desperate to land a frontman to support Marcus Rashford and Co, and with Anthony Martial now ruled out of Saturday’s FA Cup final, their need has become more apparent.
Fernandes, 28, added: “He surprised me in the national team, not only me but the rest of my team-mates. He’s physically strong, he’s still young and he’s going to get better.
“If he continues to work as he has been doing, I think he has the potential to be one of the best strikers in the world, but he needs to go to a more competitive league to prove it.”
Ramos has already proved there is life for Portugal after Cristiano Ronaldo, and given Fernandes’ praise, should he land at Old Trafford he may do the same there.
He is one of six strikers on their shortlist if they cannot sign Harry Kane, according to reports.
The likes of Victor Osimhen and Randal Kolo Muani are heading this list.
This being said, United and Kane are desperate to seal a deal.
SunSport have revealed Kane is willing to run down his contract at Tottenham and leave for FREE next summer if he is not sold.