Lux was on the ground for several minutes writhing in pain, before being taken off the field on the back of a golf cart.
“We don’t know anything yet,” Andrew Friedman, the Dodgers’ president of baseball operations, said of Lux’s injury.
After hitting a single and advancing to second on a walk, Lux broke for third on a ground ball hit by Luke Williams toward third base.
As Padres third baseman Jantzen Witte threw to second, Lux seemed to try and duck out of the way of the ball.
That’s when his knee buckled, appearing to bend backward and sending him tumbling into third base.
Lux immediately grabbed his knee as he rolled on the ground in pain. Third base coach Dino Ebel motioned for a trainer right away.
Manager Dave Roberts knelt down to Lux as he was treated on the field.
Lux was helped to his feet, then hobbled onto the back of the golf cart.
Coming into the spring, Lux was slated to be a major part of the roster in 2023, transitioning to become the team’s starting shortstop — Trea Turner’s successor in the role — after spending last season at second base.
This is a developing story and will be updated.