Trailing 3-1, Vatrano scored his second goal with 1:23 left in the second period.

The Ducks then dominated early in the third period. Henrique tied it on a feed from Denver native Troy Terry at 9:42. And McTavish put the Ducks ahead when his shot trickled past Pavel Francouz.

The Avalanche had numerous chances late, twice hitting the post until Vatrano scored an empty-net goal for his third career hat trick.

John Gibson stopped 40 shots as the Ducks, in last place in the Pacific Division, finished a six-game trip 3-2-1.

Mikko Rantanen scored twice, Samuel Girard added a goal and an assist and Cale Makar had an assist in his return from injury, but the Avs fell to fourth in the Central Division, a point behind Minnesota.

Francouz made 27 saves.

Makar had missed four games with an upper-body injury. But his return coincided with Valeri Nichushkin (upper body) sitting out.

Nathan MacKinnon fed Girard 1:13 into the second period for his 40th assist to put the Avs ahead 2-1. Then with Colorado on the power play after Gibson was called for intentionally dislodging the net, Rantanen rocketed a one-timer for his 34th goal.

It took the Avs, who had not trailed during their win streak, just 3:56 to go ahead when Rantanen knocked Makar’s rebound into an open net. It was Makar’s 31st assist.

Despite being outshot 18-7 in the first, Vatrano tied it for the Ducks midway through the period when he converted his own fat rebound.

Vatrano scored again to give Anaheim momentum entering the third. His hat trick gave him five goals in five games.